A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses
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DOI: 10.26508/lsa.202000874
Abstract: Progranulin deficiency leads to decreased levels of human APP and Aβ in a sex- and age-dependent manner and enhanced inflammatory and lysosomal responses in the plaque-associated microglia. Haploinsufficiency of progranulin (PGRN) is a leading cause… read more here.
Keywords: progranulin regulating; role progranulin; progranulin; pgrn ... See more keywords
The role of progranulin (PGRN) in the modulation of anti-inflammatory response in asthma
Sign Up to like & getrecommendations! Published in 2019 at "Central-European Journal of Immunology"
DOI: 10.5114/ceji.2019.83267
Abstract: Asthma is one of the most common chronic diseases. Epidemiological studies show that asthma will develop among around 40% of children under six years old with symptoms of bronchial obstruction. Diagnosis of asthma is complicated,… read more here.
Keywords: anti inflammatory; pgrn modulation; progranulin pgrn; role progranulin ... See more keywords