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Published in 2020 at "Cell Death Discovery"
DOI: 10.1038/s41420-020-00341-8
Abstract: The metabolism of the non-essential amino acid L-proline is emerging as a key pathway in the metabolic rewiring that sustains cancer cells proliferation, survival and metastatic spread. Pyrroline-5-carboxylate reductase (PYCR) and proline dehydrogenase (PRODH) enzymes,…
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Keywords:
role proline;
metabolism;
metabolism cancer;
proline metabolism ... See more keywords