The Role of Protein Acetylation in Centrosome Biology.
Sign Up to like & getrecommendations! Published in 2019 at "Results and problems in cell differentiation"
DOI: 10.1007/978-3-030-23173-6_2
Abstract: Acetylation is among the most prevalent posttranslational modifications in cells and regulates a number of physiological processes such as gene transcription, cell metabolism, and cell signaling. Although initially discovered on nuclear histones, many non-nuclear proteins… read more here.
Keywords: protein acetylation; acetylation; acetylation centrosome; biology ... See more keywords
Heparin: role in protein purification and substitution with animal-component free material
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DOI: 10.1007/s00253-018-9263-3
Abstract: Heparin is a highly sulfated polysaccharide which belongs to the family of glycosaminoglycans. It is involved in various important biological activities. The major biological purpose is the inhibition of the coagulation cascade to maintain the… read more here.
Keywords: protein; heparin; heparin protein; material ... See more keywords
Genome-wide transcriptome and translatome analyses reveal the role of protein extension and domestication in liver cancer oncogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Genetics and Genomics"
DOI: 10.1007/s00438-021-01766-1
Abstract: One gene could be transcribed to different RNA isoforms, and then produce various forms of protein sequences. This mechanism largely diversifies the cellular pool and allows natural selection to select from a wider range of… read more here.
Keywords: genome wide; domestication; cancer; liver cancer ... See more keywords
Role of protein in healthy ageing
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Integrative Medicine"
DOI: 10.1016/j.eujim.2018.09.002
Abstract: Abstract With the global increase in ageing populations, a current and future key challenge is to improve health expectancy. It is well established that normal ageing is associated with a loss of muscle mass (sarcopenia),… read more here.
Keywords: protein; healthy ageing; loss; protein healthy ... See more keywords
The role of protein SUMOylation in rheumatoid arthritis.
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DOI: 10.1016/j.jaut.2019.05.006
Abstract: Small ubiquitin-like modifier (SUMO) proteins, as a subgroup of post-translational modifiers, act to change the function of proteins. Through their interactions with different targets, immune pathways, and the responses they elicit, can be affected by… read more here.
Keywords: protein sumoylation; rheumatoid arthritis; sumoylation rheumatoid; arthritis ... See more keywords
The role of protein acetylation in carcinogenesis and targeted drug discovery
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.972312
Abstract: Protein acetylation is a reversible post-translational modification, and is involved in many biological processes in cells, such as transcriptional regulation, DNA damage repair, and energy metabolism, which is an important molecular event and is associated… read more here.
Keywords: acetylation; role protein; protein acetylation; carcinogenesis ... See more keywords
The Role of Protein Adduction in Toxic Neuropathies of Exogenous and Endogenous Origin
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DOI: 10.3390/toxics9050098
Abstract: The peripheral (axonal) neuropathy associated with repeated exposure to aliphatic and aromatic solvents that form protein-reactive γ-diketones shares some clinical and neuropathological features with certain metabolic neuropathies, including type-II diabetic neuropathy and uremic neuropathy, and… read more here.
Keywords: protein adduction; adduction toxic; toxic neuropathies; exogenous endogenous ... See more keywords