Articles with "role pten" as a keyword



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The diagnostic role of PTEN and ARID1A in serous effusions

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Published in 2017 at "Virchows Archiv"

DOI: 10.1007/s00428-017-2273-1

Abstract: The aim of this study was to analyze the diagnostic role of PTEN and ARID1A in effusion cytology. Effusions (n = 279), consisting of 226 carcinomas (70 ovarian, 64 breast, 36 lung, and 15 uterine corpus carcinomas;… read more here.

Keywords: role pten; pten; pten arid1a; diagnostic role ... See more keywords
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Perspectives on the role of PTEN in diabetic nephropathy: an update

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Published in 2020 at "Critical Reviews in Clinical Laboratory Sciences"

DOI: 10.1080/10408363.2020.1746735

Abstract: Abstract Phosphatase and tensin homolog (PTEN) is a potent tumor suppressor gene that antagonizes the proto-oncogenic phosphatidylinositol 3 kinase (PI3K)/protein kinase B (Akt) signaling pathway and governs basic cellular metabolic processes. Recently, its role in… read more here.

Keywords: role pten; perspectives role; diabetic nephropathy; role ... See more keywords
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The Role of PTEN in Epithelial–Mesenchymal Transition

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14153786

Abstract: Simple Summary The PTEN phosphatase is a ubiquitously expressed tumor suppressor, which inhibits the PI3K/AKT pathway in the cell. The PI3K/AKT pathway is considered to be one of the main signaling pathways that drives the… read more here.

Keywords: pi3k akt; mesenchymal transition; akt pathway; epithelial mesenchymal ... See more keywords