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1
Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2273-1
Abstract: The aim of this study was to analyze the diagnostic role of PTEN and ARID1A in effusion cytology. Effusions (n = 279), consisting of 226 carcinomas (70 ovarian, 64 breast, 36 lung, and 15 uterine corpus carcinomas;…
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Keywords:
role pten;
pten;
pten arid1a;
diagnostic role ... See more keywords
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1
Published in 2020 at "Critical Reviews in Clinical Laboratory Sciences"
DOI: 10.1080/10408363.2020.1746735
Abstract: Abstract Phosphatase and tensin homolog (PTEN) is a potent tumor suppressor gene that antagonizes the proto-oncogenic phosphatidylinositol 3 kinase (PI3K)/protein kinase B (Akt) signaling pathway and governs basic cellular metabolic processes. Recently, its role in…
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Keywords:
role pten;
perspectives role;
diabetic nephropathy;
role ... See more keywords
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2
Published in 2022 at "Cancers"
DOI: 10.3390/cancers14153786
Abstract: Simple Summary The PTEN phosphatase is a ubiquitously expressed tumor suppressor, which inhibits the PI3K/AKT pathway in the cell. The PI3K/AKT pathway is considered to be one of the main signaling pathways that drives the…
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Keywords:
pi3k akt;
mesenchymal transition;
akt pathway;
epithelial mesenchymal ... See more keywords