Role of pyroptosis in cancer cells and clinical applications.
Sign Up to like & getrecommendations! Published in 2021 at "Biochimie"
DOI: 10.1016/j.biochi.2021.03.007
Abstract: Chemotherapy drugs usually inhibit tumor cell growth through the apoptosis pathway. However, tumor cells become resistant to chemotherapy drugs by evading apoptosis. It is necessary to find new ways to inhibit tumor growth through other… read more here.
Keywords: pyroptosis cancer; pyroptosis; role pyroptosis; role ... See more keywords
Role of pyroptosis in cardiovascular disease
Sign Up to like & getrecommendations! Published in 2019 at "Cell Proliferation"
DOI: 10.1111/cpr.12563
Abstract: Cardiac function is determined by the dynamic equilibrium of various cell types and the extracellular matrix that composes the heart. Cardiovascular diseases (CVDs), especially atherosclerosis and myocardial infarction, are often accompanied by cell death and… read more here.
Keywords: pyroptosis cardiovascular; pyroptosis; role pyroptosis; cardiovascular disease ... See more keywords
Role of Pyroptosis in Respiratory Diseases and its Therapeutic Potential
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s352563
Abstract: Abstract Pyroptosis is an inflammatory type of regulated cell death that is dependent on inflammasome activation and downstream proteases such as caspase-1 or caspase 4/5/11. The main executors are gasdermins, which have an inherent pore-forming… read more here.
Keywords: pyroptosis; role pyroptosis; diseases therapeutic; respiratory diseases ... See more keywords
The role of pyroptosis in endothelial dysfunction induced by diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1093985
Abstract: Most organs in the body rely on blood flow, and vesicular damage is the leading cause of injury in multiple organs. The endothelium, as the barriers of vessels, play a critical role in ensuring vascular… read more here.
Keywords: pyroptosis endothelial; role; dysfunction induced; pyroptosis ... See more keywords