Role of Rab GTPases in Alzheimer's Disease.
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DOI: 10.1021/acschemneuro.8b00387
Abstract: Alzheimer's disease (AD) comprises two major pathological hallmarks: extraneuronal deposition of β-amyloid (Aβ) peptides ("senile plaques") and intraneuronal aggregation of the microtubule-associated protein tau ("neurofibrillary tangles"). Aβ is derived from sequential cleavage of the β-amyloid… read more here.
Keywords: alzheimer disease; rab; rab gtpases; role rab ... See more keywords