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Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.01.006
Abstract: Abstract Intestinal mucositis (IM) is a common side effect of irinotecan‐based chemotherapy. The involvement of inflammatory mediators, such as TNF‐&agr;, IL1‐&bgr;, IL‐18 and IL‐33, has been demonstrated. However, the role of adaptive immune system cells,…
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Keywords:
irinotecan induced;
intestinal mucositis;
regulatory cells;
role ... See more keywords
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Published in 2020 at "Immunological investigations"
DOI: 10.1080/08820139.2020.1832114
Abstract: BACKGROUND AND OBJECTIVES The aim of this study was to evaluate the role of T- and B-regulatory cells (Tregs and Bregs) in the pathogenesis of idiopathic granulomatous mastitis (IGM). METHODS This study includes 47 patients…
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Keywords:
cd3 cd4;
group;
regulatory cells;
idiopathic granulomatous ... See more keywords
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Published in 2020 at "British Journal of Dermatology"
DOI: 10.1111/bjd.19380
Abstract: Psoriasis is a chronic inflammatory disease with a strong genetic component that can be triggered by environmental factors. Disease pathogenesis is mainly driven by type 1 and type 17 cytokine‐producing cells which, in healthy individuals,…
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Keywords:
treatment;
regulatory cells;
pathogenesis;
psoriasis ... See more keywords
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Published in 2019 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13012
Abstract: To explore the role of regulatory T (Treg) cells in the establishment of immune tolerance induced by donor‐specific transfusion (DST) in mice with skin‐heart transplantation.
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Keywords:
immune tolerance;
skin heart;
specific transfusion;
heart transplantation ... See more keywords
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Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e24009
Abstract: e24009Background: Distant metastasis is the main cause of colorectal cancer (CRC)-related mortality, but the underlying mechanism remains largely elusive. It has been revealed that acidic microenvi...
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Keywords:
metastasis;
regulatory mechanism;
colorectal cancer;
role regulatory ... See more keywords
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Published in 2018 at "Current pharmaceutical design"
DOI: 10.2174/1381612824666180829094315
Abstract: Reducing infant mortality due to infectious diseases is one of the most important public health goals worldwide. Several approaches have been implemented to reach this goal and vaccination has been an effective strategy for reducing…
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Keywords:
regulatory cells;
cells infection;
vaccination;
infection vaccination ... See more keywords
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Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.962774
Abstract: N6-methyladenosine (m6A) modification regulates RNA translation, splicing, transport, localization, and stability at the post-transcriptional level. The m6A modification has been reported to have a wide range of effects on the nervous system, including neurogenesis, cerebellar…
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Keywords:
system;
role regulatory;
mechanism m6a;
nervous system ... See more keywords
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Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.616949
Abstract: The immune system is a tightly regulated network which allows the development of defense mechanisms against foreign antigens and tolerance toward self-antigens. Regulatory T cells (Treg) contribute to immune homeostasis by maintaining unresponsiveness to self-antigens…
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Keywords:
complex role;
cells immunity;
immunity aging;
regulatory cells ... See more keywords
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Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1019543
Abstract: Autophagy, an evolutionarily conserved cellular degradation pathway in eukaryotes, is hierarchically regulated by autophagy-related genes (Atgs). The Atg1/ULK1 complex is the most upstream factor involved in autophagy initiation. Here,we summarize the recent studies on the…
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Keywords:
mechanism atg1;
crucial role;
role regulatory;
ulk1 complex ... See more keywords