Articles with "role regulatory" as a keyword



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Role of regulatory T cells in irinotecan‐induced intestinal mucositis

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Published in 2018 at "European Journal of Pharmaceutical Sciences"

DOI: 10.1016/j.ejps.2018.01.006

Abstract: Abstract Intestinal mucositis (IM) is a common side effect of irinotecan‐based chemotherapy. The involvement of inflammatory mediators, such as TNF‐&agr;, IL1‐&bgr;, IL‐18 and IL‐33, has been demonstrated. However, the role of adaptive immune system cells,… read more here.

Keywords: irinotecan induced; intestinal mucositis; regulatory cells; role ... See more keywords
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The Role of Regulatory T and B Cells in the Etiopathogenesis of Idiopathic Granulomatous Mastitis.

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Published in 2020 at "Immunological investigations"

DOI: 10.1080/08820139.2020.1832114

Abstract: BACKGROUND AND OBJECTIVES The aim of this study was to evaluate the role of T- and B-regulatory cells (Tregs and Bregs) in the pathogenesis of idiopathic granulomatous mastitis (IGM). METHODS This study includes 47 patients… read more here.

Keywords: cd3 cd4; group; regulatory cells; idiopathic granulomatous ... See more keywords
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Role of regulatory T cells in psoriasis pathogenesis and treatment

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Published in 2020 at "British Journal of Dermatology"

DOI: 10.1111/bjd.19380

Abstract: Psoriasis is a chronic inflammatory disease with a strong genetic component that can be triggered by environmental factors. Disease pathogenesis is mainly driven by type 1 and type 17 cytokine‐producing cells which, in healthy individuals,… read more here.

Keywords: treatment; regulatory cells; pathogenesis; psoriasis ... See more keywords
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Role of regulatory T cells in CD47/donor‐specific transfusion‐induced immune tolerance in skin‐heart transplantation mice

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Published in 2019 at "Transplant Infectious Disease"

DOI: 10.1111/tid.13012

Abstract: To explore the role of regulatory T (Treg) cells in the establishment of immune tolerance induced by donor‐specific transfusion (DST) in mice with skin‐heart transplantation. read more here.

Keywords: immune tolerance; skin heart; specific transfusion; heart transplantation ... See more keywords
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The role and regulatory mechanism of NFIB in the metastasis of colorectal cancer.

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Published in 2018 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2018.36.15_suppl.e24009

Abstract: e24009Background: Distant metastasis is the main cause of colorectal cancer (CRC)-related mortality, but the underlying mechanism remains largely elusive. It has been revealed that acidic microenvi... read more here.

Keywords: metastasis; regulatory mechanism; colorectal cancer; role regulatory ... See more keywords
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Role of Regulatory T Cells in Infection and Vaccination During Early Infancy.

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Published in 2018 at "Current pharmaceutical design"

DOI: 10.2174/1381612824666180829094315

Abstract: Reducing infant mortality due to infectious diseases is one of the most important public health goals worldwide. Several approaches have been implemented to reach this goal and vaccination has been an effective strategy for reducing… read more here.

Keywords: regulatory cells; cells infection; vaccination; infection vaccination ... See more keywords
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The role and regulatory mechanism of m6A methylation in the nervous system

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.962774

Abstract: N6-methyladenosine (m6A) modification regulates RNA translation, splicing, transport, localization, and stability at the post-transcriptional level. The m6A modification has been reported to have a wide range of effects on the nervous system, including neurogenesis, cerebellar… read more here.

Keywords: system; role regulatory; mechanism m6a; nervous system ... See more keywords
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The Complex Role of Regulatory T Cells in Immunity and Aging

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Published in 2020 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2020.616949

Abstract: The immune system is a tightly regulated network which allows the development of defense mechanisms against foreign antigens and tolerance toward self-antigens. Regulatory T cells (Treg) contribute to immune homeostasis by maintaining unresponsiveness to self-antigens… read more here.

Keywords: complex role; cells immunity; immunity aging; regulatory cells ... See more keywords
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The crucial role of the regulatory mechanism of the Atg1/ULK1 complex in fungi

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Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2022.1019543

Abstract: Autophagy, an evolutionarily conserved cellular degradation pathway in eukaryotes, is hierarchically regulated by autophagy-related genes (Atgs). The Atg1/ULK1 complex is the most upstream factor involved in autophagy initiation. Here,we summarize the recent studies on the… read more here.

Keywords: mechanism atg1; crucial role; role regulatory; ulk1 complex ... See more keywords