Role of the P2 residue of human alpha 1-antitrypsin in determining target protease specificity
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DOI: 10.1371/journal.pone.0185074
Abstract: Alpha 1-antitrypsin (A1AT) is a serine protease inhibitor that mainly inhibits neutrophil elastase in the lungs. A variant of A1AT at the P1 position with methionine 358 to arginine (A1AT-Pittsburgh) is a rapid inhibitor of… read more here.
Keywords: alpha antitrypsin; role residue; role; a1at ... See more keywords