Expanding role of ribosome‐inactivating proteins: From toxins to therapeutics
Sign Up to like & getrecommendations! Published in 2022 at "IUBMB Life"
DOI: 10.1002/iub.2675
Abstract: Ribosome‐inactivating proteins (RIPs) are toxic proteins with N‐glycosidase activity. RIPs exert their action by removing a specific purine from 28S rRNA, thereby, irreversibly inhibiting the process of protein synthesis. RIPs can target both prokaryotic and… read more here.
Keywords: ribosome inactivating; expanding role; inactivating proteins; role ribosome ... See more keywords
An emerging role for the ribosome as a nexus for post-translational modifications.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2017.02.010
Abstract: The ribosome is one of life's most ancient molecular machines that has historically been viewed as a backstage participant in gene regulation, translating the genetic code across all kingdoms of life in a rote-like fashion.… read more here.
Keywords: role ribosome; translational modifications; post translational; emerging role ... See more keywords