Articles with "role senescence" as a keyword



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The potential role of senescence in limiting fibrosis caused by aging

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.29313

Abstract: Fibrosisā€related diseases carry with them a high mortality rate and their morbidity increases with age. Recent findings indicate that induced senescence in myofibroblasts can limit or reduce myocardial fibrosis, cirrhosis, and idiopathic pulmonary fibrosis, while… read more here.

Keywords: fibrosis; senescence limiting; senescent cells; senescence ... See more keywords
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Potential role of senescence in radiation-induced damage of the aged skeleton.

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Published in 2019 at "Bone"

DOI: 10.1016/j.bone.2018.12.006

Abstract: Human aging-related changes are exacerbated in cases of disease and cancer, and conversely aging is a catalyst for the occurrence of disease and multimorbidity. For example, old age is the most significant risk factor for… read more here.

Keywords: radiation induced; induced damage; damage; role senescence ... See more keywords
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The Emerging Role of Senescence in Ocular Disease

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Published in 2020 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2020/2583601

Abstract: Cellular senescence is a state of irreversible cell cycle arrest in response to an array of cellular stresses. An important role for senescence has been shown for a number of pathophysiological conditions that include cardiovascular… read more here.

Keywords: age related; emerging role; senescence; disease ... See more keywords
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The Potential Role of Senescence As a Modulator of Platelets and Tumorigenesis

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Published in 2017 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2017.00188

Abstract: In addition to thrombus formation, alterations in platelet function are frequently observed in cancer patients. Importantly, both thrombus and tumor formation are influenced by age, although the mechanisms through which physiological aging modulates these processes… read more here.

Keywords: senescent cells; senescence; platelets tumorigenesis; role senescence ... See more keywords