A novel role for SHARPIN in amyloid-β phagocytosis and inflammation by peripheral blood-derived macrophages in Alzheimer's disease
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DOI: 10.1016/j.neurobiolaging.2020.02.001
Abstract: Defective immune cell-mediated clearance of amyloid-beta (Aβ) and Aβ-associated inflammatory activation of immune cells are key contributors in pathogenesis of Alzheimer's disease (AD). However, the underlying mechanisms remain elusive. Shank-associated RH domain-interacting protein (SHARPIN) is… read more here.
Keywords: phagocytosis; alzheimer disease; blood; sharpin ... See more keywords