Role of sialylation of N-linked glycans in prion pathogenesis.
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DOI: 10.1007/s00441-022-03584-2
Abstract: Mammalian prion or PrPSc is a proteinaceous infectious agent that consists of a misfolded, self-replicating state of the prion protein or PrPC. PrPC and PrPSc are posttranslationally modified with N-linked glycans, which are sialylated at… read more here.
Keywords: role sialylation; linked glycans; strain; prion ... See more keywords