The role of Sirt6 in osteoarthritis and its effect on macrophage polarization.
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2059610
Abstract: Osteoarthritis (OA), the commonest arthritis type, features irreversible cartilage loss and synovitis. It was reported that macrophages have an important function in synovial inflammation, and our team revealed that the amounts of Sirt6, a nicotinamide… read more here.
Keywords: macrophage polarization; synovial inflammation; role sirt6; polarization ... See more keywords
The role of SIRT6 in tumors
Sign Up to like & getrecommendations! Published in 2018 at "Haematologica"
DOI: 10.3324/haematol.2017.182675
Abstract: Dysfunctional DNA-damage response and consequent genomic instability play a pivotal role in the initiation and progression of both solid and hematologic tumors. Preservation of DNA integrity is, in fact, a key cellular function, hence several… read more here.
Keywords: role sirt6; role; sirt6 tumors;