A distinct role of STING in regulating glucose homeostasis through insulin sensitivity and insulin secretion
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2101848119
Abstract: Significance The role of STING in maintaining glucose homeostasis remains unknown. Herein, using global and β-cell–specific STING knockout mouse models, we revealed a distinct role of STING in the regulation of glucose homeostasis through β-cells… read more here.
Keywords: role sting; cell; glucose homeostasis; insulin ... See more keywords
A fast-growing dengue virus mutant reveals a dual role of STING in response to infection
Sign Up to like & getrecommendations! Published in 2022 at "Open Biology"
DOI: 10.1098/rsob.220227
Abstract: The four dengue viruses (DENVs) have evolved multiple mechanisms to ensure its survival. Among these mechanisms is the ability to regulate its replication rate, which may contribute to avoiding premature immune activation that limit infection… read more here.
Keywords: replication; dengue; infection; role sting ... See more keywords
The Role of STING in Liver Injury Is Both Stimulus- and Time-Dependent
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14194029
Abstract: STING, Tmem173, is involved in liver injury caused by both infectious and sterile inflammatory models. Its role in toxic liver injury and non-alcoholic fatty liver disease (NAFLD), however, is less clear. While a few groups… read more here.
Keywords: toxic liver; liver injury; tmem173gt mice; role sting ... See more keywords