AMBRA1 and its role as a target for anticancer therapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.946086
Abstract: The activating molecule in Beclin1-regulated autophagy protein 1 (AMBRA1) is an intrinsically disordered protein that regulates the survival and death of cancer cells by modulating autophagy. Although the roles of autophagy in cancer are controversial… read more here.
Keywords: target anticancer; ambra1 role; therapy ambra1; therapy ... See more keywords
USP30: Structure, Emerging Physiological Role, and Target Inhibition
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.851654
Abstract: Ubiquitin-specific protease 30 (USP30) is a deubiquitinating enzyme (DUB) belonging to the USP subfamily, which was found localized in the mitochondrial outer membrane and peroxisomes owing to its unique transmembrane domain. Structural study revealed that… read more here.
Keywords: emerging physiological; structure; role; physiological role ... See more keywords