The Role of Telomeres in Human Disease
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of genomics and human genetics"
DOI: 10.1146/annurev-genom-010422-091101
Abstract: Telomere biology was first studied in maize, ciliates, yeast, and mice, and in recent decades, it has informed understanding of common disease mechanisms with broad implications for patient care. Short telomere syndromes are the most… read more here.
Keywords: disease; role telomeres; telomeres human; cancer ... See more keywords
Role of Telomeres and Telomeric Proteins in Human Malignancies and Their Therapeutic Potential
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12071901
Abstract: Telomeres are the ends of linear chromosomes comprised of repetitive nucleotide sequences in humans. Telomeres preserve chromosomal stability and genomic integrity. Telomere length shortens with every cell division in somatic cells, eventually resulting in replicative… read more here.
Keywords: role telomeres; human malignancies; role; telomeric proteins ... See more keywords