The role of TLR4/NF-κB signaling in the radioprotective effects of exogenous Prdx6.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.108830
Abstract: Peroxiredoxin 6 (Prdx6) is a bifunctional enzyme with multi-substrate peroxidase and phospholipase activities that is involved in cell redox homeostasis and regulates intracellular processes. Previously, recombinant Prdx6 was shown to exert a radioprotective effect during… read more here.
Keywords: role tlr4; radioprotective effect; prdx6; tlr4 ... See more keywords
Role of TLR4 in the induction of inflammatory changes in adipocytes and macrophages
Sign Up to like & getrecommendations! Published in 2020 at "Adipocyte"
DOI: 10.1080/21623945.2020.1760674
Abstract: ABSTRACT In obesity, high levels of saturated fatty acids (SFAs) contribute to adipose tissue inflammation and dysfunction. Obesity-induced macrophage infiltration leads to insulin resistance, but the adipocyte itself may play a role in generating the… read more here.
Keywords: inflammatory changes; tlr4 induction; role tlr4; induction inflammatory ... See more keywords
Pathophysiological Role of TLR4 in Chronic Relapsing Itch Induced by Subcutaneous Capsaicin Injection in Neonatal Rats
Sign Up to like & getrecommendations! Published in 2022 at "Immune Network"
DOI: 10.4110/in.2022.22.e20
Abstract: Despite the high prevalence of chronic dermatitis and the accompanied intractable itch, therapeutics that specifically target itching have low efficacy. Increasing evidence suggests that TLRs contribute to immune activation and neural sensitization; however, their roles… read more here.
Keywords: subcutaneous capsaicin; itch; tlr4 antagonist; tlr4 ... See more keywords