Role of TRIM33 in Wnt signaling during mesendoderm differentiation
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DOI: 10.1007/s11427-017-9129-3
Abstract: Tripartite motif 33 (TRIM33), a member of the transcription intermediate factor 1 (TIF1) family of transcription cofactors, mediates transforming growth factor-beta (TGF-β) signaling through its PHD-Bromo cassette in mesendoderm differentiation during early mouse embryonic development.… read more here.
Keywords: mesendoderm differentiation; trim33; wnt signaling; role trim33 ... See more keywords
TRIM33 deficiency in monocytes and macrophages impairs resolution of colonic inflammation
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DOI: 10.1016/j.ebiom.2019.05.037
Abstract: Background Mature myeloid cells play a crucial role in Crohn's disease (CD) but the molecular players that regulate their functions in CD are not fully characterized. We and others have shown that TRIM33 is involved… read more here.
Keywords: role trim33; colonic inflammation; trim33; inflammation ... See more keywords