Articles with "roles aml" as a keyword



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EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environment

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Published in 2022 at "Blood Advances"

DOI: 10.1182/bloodadvances.2022008018

Abstract: Key Points • EVI1 exerts distinct roles in AML, including resistance, pathogenicity of aggressive diseases independent of stemness, and immune evasion.• ERG and cyclin D1 are leukemia-specific targets of EVI1, providing potential therapeutic vulnerability of… read more here.

Keywords: roles aml; erg cyclin; evi1 exerts; exerts distinct ... See more keywords