The Cellular and Developmental Roles of Cullins, Neddylation, and the COP9 Signalosome in Dictyostelium discoideum
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DOI: 10.3389/fphys.2022.827435
Abstract: “Cullins (CULs) are a core components” of cullin-RING E3 ubiquitin ligases (CRLs), which regulate the degradation, function, and subcellular trafficking of proteins. CULs are post-translationally regulated through neddylation, a process that conjugates the ubiquitin-like modifier… read more here.
Keywords: cellular developmental; cop9 signalosome; roles cullins; cullins neddylation ... See more keywords