Current insights into the functional roles of ferroptosis in musculoskeletal diseases and therapeutic implications
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1112751
Abstract: Ferroptosis is a novel type of cell death associated with iron accumulation and excessive lipid peroxidation. Elucidating the underlying molecular mechanisms of ferroptosis is intensively related to the development and treatment of multiple diseases, including… read more here.
Keywords: ferroptosis musculoskeletal; musculoskeletal diseases; current insights; functional roles ... See more keywords
Multifaceted Roles of Ferroptosis in Lung Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.919187
Abstract: Ferroptosis is a distinct type of programmed cell death (PCD) that depends on iron and is characterized by the accumulation of intracellular iron, exhaustion of glutathione, deactivation of glutathione peroxidase, and promotion of lipid peroxidation.… read more here.
Keywords: lung diseases; lung; ferroptosis lung; multifaceted roles ... See more keywords
The Emerging Roles of Ferroptosis in Vascular Cognitive Impairment
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.00811
Abstract: Vascular cognitive impairment (VCI) is a clinical syndrome that encompasses all forms of cognitive deficits caused by cerebrovascular disease, from mild cognitive impairment to dementia. Vascular dementia, the second most common type of dementia after… read more here.
Keywords: emerging roles; vascular cognitive; roles ferroptosis; cognitive impairment ... See more keywords
ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14235896
Abstract: Simple Summary The dysregulation of ACSL3 and ACSL4, which belong to the long-chain fatty acyl CoA synthetase family (ACSLs), affects the behavior of various cancer cells. This review presents their distinct roles in ferroptosis and… read more here.
Keywords: acsl3 acsl4; cancers acsl3; roles ferroptosis; ferroptosis ... See more keywords