Multifaceted Roles of the KEAP1–NRF2 System in Cancer and Inflammatory Disease Milieu
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DOI: 10.3390/antiox11030538
Abstract: In a multicellular environment, many different types of cells interact with each other. The KEAP1–NRF2 system defends against electrophilic and oxidative stresses in various types of cells. However, the KEAP1–NRF2 system also regulates the expression… read more here.
Keywords: system; keap1 nrf2; roles keap1; nrf2 system ... See more keywords
Pleiotropic Roles of a KEAP1-Associated Deubiquitinase, OTUD1
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020350
Abstract: Protein ubiquitination, which is catalyzed by ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin ligases, is a crucial post-translational modification to regulate numerous cellular functions in a spatio–temporal-specific manner. The human genome encodes ~100 deubiquitinating enzymes (DUBs),… read more here.
Keywords: pleiotropic roles; associated deubiquitinase; otud1; roles keap1 ... See more keywords