Articles with "roles lrrk2" as a keyword



Roles of LRRK2 and its orthologs in protecting against neurodegeneration and neurodevelopmental defects

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Published in 2025 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2025.1569733

Abstract: In humans, variants in the LRRK2 gene are the most prevalent risk factors for Parkinson’s disease (PD). Whereas studies in model organisms have long indicated that the orthologs of the wild-type LRRK proteins protect against… read more here.

Keywords: lrrk2 orthologs; lrrk proteins; roles lrrk2; neurodegeneration neurodevelopmental ... See more keywords