The roles and mechanisms of circular RNAs related to mTOR in cancers
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24783
Abstract: Circular RNAs (circRNAs) are stable molecules with covalently closed structures that have an irreplaceable role in the occurrence, progression, and even treatment of plenty of cancers. Mammalian/mechanistic target of rapamycin (mTOR) is a key regulator… read more here.
Keywords: rnas related; mechanisms circular; circular rnas; roles mechanisms ... See more keywords
The Tumor Suppressor Roles and Mechanisms of MiR-491 in Human Cancers.
Sign Up to like & getrecommendations! Published in 2022 at "DNA and cell biology"
DOI: 10.1089/dna.2022.0274
Abstract: MicroRNAs (miRNAs) are short non-coding RNAs that bind to the 3' untranslated region (3'' UTR) of target mRNAs to control gene expression post-transcriptionally. Recent indications have highlighted their important roles in a variety of pathophysiological… read more here.
Keywords: tumor suppressor; mir 491; roles mechanisms; human cancers ... See more keywords
Exosomes in gastric cancer: roles, mechanisms, and applications
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer"
DOI: 10.1186/s12943-019-1001-7
Abstract: Exosomes are nanosized extracellular vesicles that can be released by almost all types of cells. Initially considered as the garbage bins acting to discard unwanted products of cells, exosomes are now recognized as an important… read more here.
Keywords: cancer roles; exosomes gastric; gastric cancer; roles mechanisms ... See more keywords
The roles and mechanisms of gut microbiome and metabolome in patients with cerebral infarction
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1112148
Abstract: As the most common type of stroke, ischemic stroke, also known as cerebral infarction (CI), with its high mortality and disability rate, has placed a huge burden on social economy and public health. Treatment methods… read more here.
Keywords: mechanisms gut; intestinal microbiota; roles mechanisms; cerebral infarction ... See more keywords
The roles and mechanisms of epigenetic regulation in pathological myocardial remodeling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.952949
Abstract: Pathological myocardial remodeling was still one of the leading causes of death worldwide with an unmet therapeutic need. A growing number of researchers have addressed the role of epigenome changes in cardiovascular diseases, paving the… read more here.
Keywords: mechanisms epigenetic; pathological myocardial; roles mechanisms; epigenetic regulation ... See more keywords
Roles and mechanisms of garlic and its extracts on atherosclerosis: A review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.954938
Abstract: The prevention and treatment of cardiovascular diseases (CVDs) have achieved initial results, but the number of CVDs patients will increase rapidly in the next 10 years. Atherosclerosis (AS) is a significant risk factor for CVDs.… read more here.
Keywords: extracts atherosclerosis; prevention; garlic extracts; roles mechanisms ... See more keywords
An Evaluation of the In Vitro Roles and Mechanisms of Silibinin in Reducing Pyrazinamide- and Isoniazid-Induced Hepatocellular Damage
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21103714
Abstract: Tuberculosis remains a significant infectious lung disease that affects millions of patients worldwide. Despite numerous existing drug regimens for tuberculosis, drug-induced liver injury is a major challenge that limits the effectiveness of these therapeutics. Two… read more here.
Keywords: evaluation vitro; isoniazid; vitro roles; damage ... See more keywords
Insight into the Biological Roles and Mechanisms of Phytochemicals in Different Types of Cancer: Targeting Cancer Therapeutics
Sign Up to like & getrecommendations! Published in 2023 at "Nutrients"
DOI: 10.3390/nu15071704
Abstract: Cancer is a hard-to-treat disease with a high reoccurrence rate that affects health and lives globally. The condition has a high occurrence rate and is the second leading cause of mortality after cardiovascular disorders. Increased… read more here.
Keywords: mechanisms phytochemicals; roles mechanisms; biological roles; insight biological ... See more keywords
Protective Roles and Mechanisms of Taurine on Myocardial Hypoxia/Reoxygenation-Induced Apoptosis.
Sign Up to like & getrecommendations! Published in 2019 at "Acta Cardiologica Sinica"
DOI: 10.6515/acs.201907_35(4).20181218a
Abstract: Background This study aimed to investigate the protective roles and mechanisms of taurine on myocardial ischemia/reperfusion (I/R)-induced cell apoptosis, and thus provide evidence for the treatment of myocardial I/R injury and the development of related… read more here.
Keywords: mechanisms taurine; protective roles; roles mechanisms; taurine myocardial ... See more keywords