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   Articles with "roles micrornas" as a keyword



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Emerging roles of microRNAs in regulating the mTOR signaling pathway during tumorigenesis

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recommendations! Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.28401

Abstract: The mammalian target of rapamycin (mTOR) is a large Ser/Thr protein kinase that belongs to the phosphoinositide 3‐kinase (PI3K) family and mediates various physiological and pathological processes, especially cell proliferation, protein synthesis, autophagy, and cancer… read more here.

Keywords: emerging roles; mtor signaling; regulating mtor; micrornas regulating ... See more keywords
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Roles of microRNAs in preeclampsia

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recommendations! Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.27291

Abstract: Preeclampsia (PE) is a complex disorder that is characterized by hypertension and proteinuria after the 20th week of pregnancy, and it causes most neonatal morbidity and perinatal mortality. Most studies suggest that placental dysfunction is… read more here.

Keywords: mirna; micrornas preeclampsia; physiology; preeclampsia ... See more keywords
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Antitumor and Protective Effects of Melatonin: The Potential Roles of MicroRNAs.

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recommendations! Published in 2021 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-030-73234-9_31

Abstract: MicroRNAs (miRNAs) are endogenous short noncoding RNAs with approximately 22 nucleotides. The primary function of miRNAs is the negative regulation of target gene expression via mRNA degradation or translation inhibition. During recent years, much attention… read more here.

Keywords: effects melatonin; antitumor protective; roles micrornas; potential roles ... See more keywords
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Roles of microRNAs in chronic pediatric diseases and their use as potential biomarkers: A review.

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recommendations! Published in 2021 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2021.108763

Abstract: MicroRNAs (miRNAs) are small non-coding highly conserved RNA molecules that can act as master regulators of gene expression in a sequence-specific manner either by translation repression or mRNA degradation, influencing a wide range of biologic… read more here.

Keywords: micrornas chronic; use potential; pediatric diseases; roles micrornas ... See more keywords
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The roles of microRNAs in the pathogenesis of chronic obstructive pulmonary disease.

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recommendations! Published in 2019 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2018.12.013

Abstract: Chronic obstructive pulmonary disease (COPD) is characterized by a progressive and irreversible airflow obstruction, with an abnormal lung function. The etiology of COPD correlates with complex interactions between environmental and genetic determinants. However, the exact… read more here.

Keywords: chronic obstructive; obstructive pulmonary; disease; pathogenesis ... See more keywords
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The regulatory roles of microRNAs toward pathogenesis and treatments in Huntington's disease

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recommendations! Published in 2021 at "Journal of Biomedical Science"

DOI: 10.1186/s12929-021-00755-1

Abstract: Huntington’s disease (HD) is one of neurodegenerative diseases, and is defined as a monogenetic disease due to the mutation of Huntingtin gene. This disease affects several cellular functions in neurons, and further influences motor and… read more here.

Keywords: mirna; huntington disease; disease; micrornas toward ... See more keywords
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The roles of microRNAs in regulation of mammalian spermatogenesis

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recommendations! Published in 2017 at "Journal of Animal Science and Biotechnology"

DOI: 10.1186/s40104-017-0166-4

Abstract: Mammalian spermatogenesis contains three continuous and organized processes, by which spermatogonia undergo mitosis and differentiate to spermatocytes, follow on meiosis to form haploid spermatids and ultimately transform into spermatozoa. These processes require an accurately, spatially… read more here.

Keywords: spermatogenesis; roles micrornas; regulation mammalian; mammalian spermatogenesis ... See more keywords
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[Pathogenic and diagnostic roles of microRNAs in adrenocortical tumours].

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recommendations! Published in 2018 at "Orvosi hetilap"

DOI: 10.1556/650.2018.30919

Abstract: Adrenocortical tumours are quite prevalent. Most of these tumours are benign, hormonally inactive adrenocortical adenomas. Rare hormone-secreting adrenocortical adenomas are associated with severe clinical consequences, whereas the prognosis of the rare adrenocortical cancer is rather… read more here.

Keywords: adrenocortical tumours; mir; micrornas adrenocortical; pathogenic diagnostic ... See more keywords
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Multifunctional Roles of MicroRNAs in Schistosomiasis

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recommendations! Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2022.925386

Abstract: Schistosomiasis is a parasitic disease that is caused by helminths of the genus Schistosoma. The dioecious schistosomes mate and lay eggs after undergoing a complex life cycle. Schistosome eggs are mostly responsible for the transmission… read more here.

Keywords: micrornas schistosomiasis; multifunctional roles; disease; treatment schistosomiasis ... See more keywords
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Roles of microRNAs in Ovarian Cancer Tumorigenesis: Two Decades Later, What Have We Learned?

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recommendations! Published in 2020 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2020.01084

Abstract: Ovarian cancer is one of the top gynecological malignancies that cause deaths among females in the United States. At the molecular level, significant progress has been made in our understanding of ovarian cancer development and… read more here.

Keywords: micrornas ovarian; cancer tumorigenesis; ovarian cancer; roles micrornas ... See more keywords
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An Insight into the Roles of MicroRNAs and Exosomes in Sarcoma

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recommendations! Published in 2019 at "Cancers"

DOI: 10.3390/cancers11030428

Abstract: Sarcomas are rare solid tumors, but at least one-third of patients with sarcoma die from tumor-related disease. MicroRNA (miRNA) is a noncoding RNA that regulates gene expression in all cells and plays a key role… read more here.

Keywords: exosomes sarcoma; micrornas exosomes; insight roles; roles micrornas ... See more keywords