Speculating on the Roles of Nuclear Speckles: How RNA‐Protein Nuclear Assemblies Affect Gene Expression
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DOI: 10.1002/bies.202000104
Abstract: Nuclear speckles are eukaryotic nuclear bodies enriched in splicing factors. Their exact purpose has been a matter of debate. The different proposed roles of nuclear speckles are reviewed and an additional layer of function is… read more here.
Keywords: nuclear speckles; splicing factors; gene expression; roles nuclear ... See more keywords
Potential roles of nuclear receptors in mediating neurodevelopmental toxicity of known endocrine‐disrupting chemicals in ascidian embryos
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DOI: 10.1002/mrd.23219
Abstract: Endocrine Disrupting Chemicals (EDCs) are molecules able to interfere with the vertebrate hormonal system in different ways, a major one being the modification of the activity of nuclear receptors (NRs). Several NRs are expressed in… read more here.
Keywords: nuclear receptors; endocrine disrupting; potential roles; roles nuclear ... See more keywords
Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions
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DOI: 10.3390/ijms20122991
Abstract: Polyphosphoinositides (PPIns) are a family of seven lipid messengers that regulate a vast array of signalling pathways to control cell proliferation, migration, survival and differentiation. PPIns are differentially present in various sub-cellular compartments and, through… read more here.
Keywords: nuclear phosphoinositides; nuclear functions; phosphoinositides regulation; roles nuclear ... See more keywords