Emerging Roles for Phase Separation of RNA-Binding Proteins in Cellular Pathology of ALS
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.840256
Abstract: Liquid-liquid phase separation (LLPS) is emerging as a major principle for the mesoscale organization of proteins, RNAs, and membrane-bound organelles into biomolecular condensates. These condensates allow for rapid cellular responses to changes in metabolic activities… read more here.
Keywords: pathology; roles phase; phase separation; separation rna ... See more keywords
Roles of Phase Separation for Cellular Redox Maintenance
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.691946
Abstract: The oxidation reaction greatly alters characteristics of various cellular components. In exchange for efficient energy production, mitochondrial aerobic respiration substantially increases the risk of excess oxidation of cellular biomolecules such as lipids, proteins, nucleic acids,… read more here.
Keywords: roles phase; separation cellular; phase separation; redox ... See more keywords