Roles of 14-3-3β and γ in regulation of the glucocorticoid receptor transcriptional activation and hepatic gluconeogenesis.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.05.077
Abstract: The glucocorticoid receptor (GR) is a ligand-dependent transcription factor that mediates the effects of glucocorticoids, and plays a crucial role in cell growth, development, inflammation, and gluconeogenesis. The 14-3-3 proteins bind to target proteins via… read more here.
Keywords: roles regulation; regulation glucocorticoid; hepatic gluconeogenesis; gluconeogenesis ... See more keywords
G-quadruplex DNA and RNA: Their roles in regulation of DNA replication and other biological functions.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.05.132
Abstract: G-quadruplex is one of the best-studied non-B type DNA that is now known to be prevalently present in the genomes of almost all the biological species. Recent studies reveal roles of G-quadruplex (G4) structures in… read more here.
Keywords: regulation dna; dna; roles regulation; dna replication ... See more keywords
Roles and regulation of Haspin kinase and its impact on carcinogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2022.110303
Abstract: Cancer therapy is based on the selective clearance of malignant cells without severely damaging healthy tissues, and current clinical practice is constantly in need for new therapeutic targets in tumor management. The atypical protein kinase… read more here.
Keywords: haspin; roles regulation; carcinogenesis; kinase ... See more keywords
Roles and regulation of myosin V interaction with cargo.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in biological regulation"
DOI: 10.1016/j.jbior.2021.100787
Abstract: A major question in cell biology is, how are organelles and large macromolecular complexes transported within a cell? Myosin V molecular motors play critical roles in the distribution of organelles, vesicles, and mRNA. Mis-localization of… read more here.
Keywords: myosin; roles regulation; adaptor proteins; regulation myosin ... See more keywords
Roles and Regulation of Extracellular Vesicles in Cardiovascular Mineral Metabolism
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2018.00187
Abstract: Cardiovascular calcification is a multifaceted disease that is a leading independent predictor of cardiovascular morbidity and mortality. Recent studies have identified a calcification-prone population of extracellular vesicles as the putative elementary units of vascular microcalcification… read more here.
Keywords: extracellular vesicles; vesicles cardiovascular; roles regulation; calcification ... See more keywords
The Functional Roles and Regulation of Circular RNAs during Cellular Stresses
Sign Up to like & getrecommendations! Published in 2022 at "Non-Coding RNA"
DOI: 10.3390/ncrna8030038
Abstract: Circular RNAs (circRNAs) are a novel class of regulatory RNA involved in many biological, physiological and pathological processes by functioning as a molecular sponge, transcriptional/epigenetic/splicing regulator, modulator of protein–protein interactions, and a template for encoding… read more here.
Keywords: regulation circular; circular rnas; rnas cellular; regulation ... See more keywords