Novel roles for RNA binding proteins squid, hephaesteus, and Hrb27C in Drosophila oogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.550
Abstract: Reproductive capacity in many organisms is maintained by germline stem cells (GSCs). A complex regulatory network influences stem cell fate, including intrinsic factors, local signals, and hormonal and nutritional cues. Posttranscriptional regulatory mechanisms ensure proper… read more here.
Keywords: rna binding; novel roles; squid hephaesteus; proteins squid ... See more keywords
The roles of RNA processing in translating genotype to phenotype
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/nrm.2016.139
Abstract: A goal of human genetics studies is to determine the mechanisms by which genetic variation produces phenotypic differences that affect human health. Efforts in this respect have previously focused on genetic variants that affect mRNA… read more here.
Keywords: processing translating; variants affect; genotype phenotype; translating genotype ... See more keywords
Emerging roles for RNA-binding proteins as effectors and regulators of cardiovascular disease
Sign Up to like & getrecommendations! Published in 2017 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehw567
Abstract: The cardiovascular system comprises multiple cell types that possess the capacity to modulate their phenotype in response to acute or chronic injury. Transcriptional and post-transcriptional mechanisms play a key role in the regulation of remodelling… read more here.
Keywords: binding proteins; emerging roles; rna binding; disease ... See more keywords
Retracted: Integrated Analysis of the Roles of RNA Binding Proteins and Their Prognostic Value in Clear Cell Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Healthcare Engineering"
DOI: 10.1155/2023/9828737
Abstract: [This retracts the article DOI: 10.1155/2021/5568411.]. read more here.
Keywords: cell; rna binding; retracted integrated; roles rna ... See more keywords
The potential roles of RNA N6-methyladenosine in atherosclerosis.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202202_28096
Abstract: OBJECTIVE Atherosclerosis, characterized by endothelial injury, multicellular involvement, chronic inflammation, and lipid deposition, can lead to acute cardiovascular events. N6-methyladenosine (m6A) is the most abundant, prevalent RNA modification in mammalian cells. m6A, a reversible modification,… read more here.
Keywords: modification; m6a modification; roles rna; atherosclerosis ... See more keywords
Pathogenic Roles of RNA-Binding Proteins in Sarcomas
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14153812
Abstract: Simple Summary DNA information can be copied into mRNA (this process is called transcription) and proteins can be subsequently synthesized using the information in mRNA as a template (called translation). Approximately 4000 RNA-binding proteins (RBPs)… read more here.
Keywords: rna binding; types sarcomas; pathogenic roles; roles rna ... See more keywords
Context-Dependent Roles of RNA Modifications in Stress Responses and Diseases
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22041949
Abstract: RNA modifications are diverse post-transcriptional modifications that regulate RNA metabolism and gene expression. RNA modifications, and the writers, erasers, and readers that catalyze these modifications, serve as important signaling machineries in cellular stress responses and… read more here.
Keywords: rna modifications; stress; responses diseases; stress responses ... See more keywords