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Roles of SAMHD1 in antiviral defense, autoimmunity and cancer

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Published in 2017 at "Reviews in Medical Virology"

DOI: 10.1002/rmv.1931

Abstract: The enzyme, sterile α motif and histidine‐aspartic acid domain–containing protein 1 (SAMHD1) diminishes infection of human immunodeficiency virus type 1 (HIV‐1) by hydrolyzing intracellular deoxynucleotide triphosphates (dNTPs) in myeloid cells and resting CD4+ T cells.… read more here.

Keywords: samhd1 antiviral; hiv; antiviral defense; samhd1 ... See more keywords