Dual roles of tumour cells-derived matrix metalloproteinase 2 on brain tumour growth and invasion
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Cancer"
DOI: 10.1038/bjc.2017.362
Abstract: Background:A previous study on a murine astrocytoma cell-line ALTS1C1 showed a highly invasive pattern similar to clinical anaplastic astrocytoma in vivo. This cell-line also expressed a high level of matrix metalloproteinase 2 (MMP2). This study… read more here.
Keywords: roles tumour; tumour growth; brain tumour; matrix metalloproteinase ... See more keywords
GCN2: roles in tumour development and progression
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Society Transactions"
DOI: 10.1042/bst20211252
Abstract: GCN2 (general control nonderepessible 2) is an eIF2α kinase responsible for entirely rewiring the metabolism of cells when they are put under amino acid starvation stress. Recently, there has been renewed interest in GCN2 as… read more here.
Keywords: gcn2; development; roles tumour; gcn2 roles ... See more keywords
Two-Front War on Cancer—Targeting TAM Receptors in Solid Tumour Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14102488
Abstract: Simple Summary In recent years, many studies have shown the importance of TAM kinases in both normal and neoplastic cells. In this review, we present and discuss the role of the TAM family (AXL, MERTK,… read more here.
Keywords: receptor tyrosine; cancer; roles tumour; war cancer ... See more keywords