Rolipram suppresses migration and invasion of human choriocarcinoma cells by inhibiting phosphodiesterase 4-mediated epithelial-mesenchymal transition.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23363
Abstract: Rolipram is a selective phosphodiesterase-4 (PDE4) inhibitor. The effect of rolipram on the metastasis of choriocarcinoma is barely known. Here, we evaluated the role of rolipram in the migration and invasion of human choriocarcinoma cells… read more here.
Keywords: choriocarcinoma cells; choriocarcinoma; rolipram; migration invasion ... See more keywords
Rolipram promotes hippocampal regeneration in mice after trimethyltin-induced neurodegeneration
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DOI: 10.1097/wnr.0000000000002072
Abstract: This study aimed to investigate the effects of rolipram, a phosphodiesterase inhibitor, on brain tissue regeneration. Trimethyltin-injected mice, an animal model of hippocampal tissue regeneration, was created by a single injection of trimethyltin chloride (2.2 mg/kg,… read more here.
Keywords: mice; rolipram; tissue regeneration; regeneration ... See more keywords
Improving the Characteristics of Fruiting Bodies in Lentinus edodes: The Impact of Rolipram-Induced cAMP Modulation
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DOI: 10.3390/metabo14110619
Abstract: Background: Strains XG04 and XGT2 of Lentinus edodes (Berk.) Singer demonstrate a high degree of genomic similarity, with XGT2 representing a systematic selection of XG04 and exhibiting enhanced phenotypic traits. Methods: An investigation into the… read more here.
Keywords: improving characteristics; rolipram; xgt2; characteristics fruiting ... See more keywords