Stimulating TRPV1 externalization and synthesis in dorsal root ganglion neurons contributes to PGE2 potentiation of TRPV1 activity and nociceptor sensitization
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pain"
DOI: 10.1002/ejp.959
Abstract: Persistent peripheral sensitization contributes to chronic pain. Plasticity of nociceptive dorsal root ganglion (DRG) neurons (nociceptors) induced by pro‐inflammatory mediators contributes to sensitization. Prostaglandin E2 (PGE2) enriched in injured tissues is known not only directly… read more here.
Keywords: root ganglion; dorsal root; trpv1 activity; sensitization ... See more keywords
The effects of low intensity focused ultrasonic stimulation on dorsal root ganglion neurons and Schwann cells in vitro
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24700
Abstract: Satisfactory treatment of peripheral nerve injury (PNI) faces difficulties owing to the intrinsic biological barriers in larger injuries and invasive surgical interventions. Injury gaps >3 cm have low chances of full motor and sensory recovery,… read more here.
Keywords: dorsal root; stimulation dorsal; root ganglion;
BET protein inhibition in macrophages enhances dorsal root ganglion neurite outgrowth in female mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25036
Abstract: Peripheral nerve regeneration is limited after injury, especially in humans, due to the large distance the axons have to grow in the limbs. This process is highly dependent on the expression of neuroinflammatory factors produced… read more here.
Keywords: female mice; inhibition; root ganglion; neurite outgrowth ... See more keywords
The role of periradicular infiltration in dorsal root ganglion stimulation for chronic neuropathic pain
Sign Up to like & getrecommendations! Published in 2021 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-021-04745-y
Abstract: Targeting the correct spinal level is essential in dorsal root ganglion (DRG) stimulation. Anatomical selection of the DRG alone is not ideal since the pain area is not necessarily confined to the borders of the… read more here.
Keywords: stimulation; root ganglion; target; dorsal root ... See more keywords
Frequency dependency of therapeutic efficacy in dorsal root ganglion stimulation for neuropathic pain
Sign Up to like & getrecommendations! Published in 2022 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-022-05161-6
Abstract: The influence of the stimulation frequency on the outcomes of dorsal root ganglion stimulation (DRG-S) to treat pain is not well understood. It is assumed that specific neural components dedicated to different tasks in the… read more here.
Keywords: dorsal root; root ganglion; ganglion stimulation; pain ... See more keywords
Pulsed radiofrequency of the C2 dorsal root ganglion and epidural steroid injections for cervicogenic headache
Sign Up to like & getrecommendations! Published in 2019 at "Neurological Sciences"
DOI: 10.1007/s10072-019-03782-x
Abstract: BackgroundCervicogenic headache (CEH) is characterized by unilateral headache symptoms referred to the head from the cervical spine. Few methods have addressed long-term pain relief for CEH. This study was undertaken to evaluate pain control and… read more here.
Keywords: esi group; root ganglion; group; dorsal root ... See more keywords
Electric Field Stimulation for the Functional Assessment of Isolated Dorsal Root Ganglion Neuron Excitability.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of biomedical engineering"
DOI: 10.1007/s10439-021-02725-y
Abstract: Genetically encoded calcium indicators have proven useful for characterizing dorsal root ganglion neuron excitability in vivo. Challenges persist in achieving high spatial-temporal resolutions in vivo, however, due to deep tissue imaging and motion artifacts that… read more here.
Keywords: root ganglion; dorsal root; neuron excitability; electric field ... See more keywords
Effects of resveratrol in the signaling of neuropathic pain involving P2X3 in the dorsal root ganglion of rats
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neurologica Belgica"
DOI: 10.1007/s13760-019-01126-2
Abstract: Neuropathic pain is a major public health problem because it has a considerable impact on life quality of patients. Neuropathic pain caused by a lesion or disease of the somatosensory nervous system, which causes unpleasant… read more here.
Keywords: root ganglion; effects resveratrol; dorsal root; neuropathic pain ... See more keywords
Association between sensory nerve action potential and lumbar dorsal root ganglion area
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2018.11.019
Abstract: OBJECTIVE To quantify the cross-sectional area (CSA) of lumbar dorsal root ganglion (DRG) by magnetic resonance imaging (MRI) and investigate the relationship between the cross-sectional area (CSA) of DRGs and sensory nerve action potentials (SNAP)… read more here.
Keywords: lumbar dorsal; sensory nerve; root ganglion; area ... See more keywords
Expression pattern of type 3 adenylyl cyclase in rodent dorsal root ganglion and its primary afferent terminals
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.10.049
Abstract: cAMP (Cyclic Adenosine monophosphate), one of the most highly studied second messengers, is regulated by a family of adenylyl cyclase (AC) enzymes. Type 3 adenylyl cyclase (abbreviated as AC3), a subtype of adenylyl cyclase, is… read more here.
Keywords: adenylyl cyclase; type adenylyl; root ganglion; dorsal root ... See more keywords
CaMK II γ down regulation protects dorsal root ganglion neurons from ropivacaine hydrochloride neurotoxicity
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-05678-2
Abstract: T-type calcium channels are intimately involved in the local anesthetics neurotoxicity. Does CaMKIIγ regulate T-type calcium currents in local anesthetics neurotoxicity? This study generated pAd-CaMKIIγ and pAd-shRNA adenovirus vectors to up- and down-regulate CaMKIIγ mRNA… read more here.
Keywords: ropivacaine hydrochloride; drg; root ganglion; dorsal root ... See more keywords