Ropivacaine Wound Infiltration for Pain Management After Breast Cancer Mastectomy: A Population Pharmacokinetic Analysis
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.452
Abstract: Ropivacaine continuous wound infusions (CWIs) are extensively used as a component of multimodal analgesia. The rational application of CWI of ropivacaine requires a thorough understanding of its pharmacokinetics to investigate the risk of potential systemic… read more here.
Keywords: ropivacaine wound; analysis; population pharmacokinetic; ropivacaine ... See more keywords
Ropivacaine inhibits proliferation and invasion and promotes apoptosis and autophagy in bladder cancer cells via inhibiting PI3K/AKT pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23233
Abstract: Application of a certain concentration of local anesthetics during tumor resection inhibits the progression of tumor. The effects of ropivacaine in bladder cancer (BC) have never been explored. We explored the effects of ropivacaine on… read more here.
Keywords: pi3k akt; proliferation; invasion; bladder cancer ... See more keywords
The Amide Local Anesthetic Ropivacaine Attenuates Acute Rejection After Allogeneic Mouse Lung Transplantation
Sign Up to like & getrecommendations! Published in 2019 at "Lung"
DOI: 10.1007/s00408-019-00197-5
Abstract: PurposeAcute allograft rejection after lung transplantation remains an unsolved hurdle. The pathogenesis includes an inflammatory response during and after transplantation. Ropivacaine, an amide-linked local anesthetic, has been shown to attenuate lung injury due to its… read more here.
Keywords: rejection; lung transplantation; ropivacaine; transplantation ... See more keywords
[Ropivacaine withdrawal syndrome: a case report].
Sign Up to like & getrecommendations! Published in 2020 at "Revista brasileira de anestesiologia"
DOI: 10.1016/j.bjan.2019.12.006
Abstract: INTRODUCTION AND OBJECTIVES Ropivacaine is a long-acting local anesthetic that causes prolonged anesthesia and is beneficial for a wide variety of surgeries. Systemic toxicity has been reported after usage of high dose ropivacaine or inadvertent… read more here.
Keywords: ropivacaine; withdrawal syndrome; ropivacaine withdrawal; case report ... See more keywords
Infrared thermography to assess dermatomal levels of labor epidural analgesia with 1 mg/mL ropivacaine plus 0.5 µg/mL sufentanil: a prospective cohort study.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of obstetric anesthesia"
DOI: 10.1016/j.ijoa.2019.08.006
Abstract: BACKGROUND Assessment of the effectiveness of obstetric epidural analgesia may be difficult and techniques for objective assessment of epidural spread of local anesthetic would be useful. In this prospective cohort study we assessed whether obstetric… read more here.
Keywords: prospective cohort; epidural analgesia; infrared thermography; ropivacaine ... See more keywords
The impact of dexamethasone as a perineural additive to ropivacaine for PECS II blockade in patients undergoing unilateral radical mastectomy - A prospective, randomized, controlled and double-blinded trial.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical anesthesia"
DOI: 10.1016/j.jclinane.2021.110622
Abstract: STUDY OBJECTIVE Dexamethasone is commonly used as an adjuvant to local anesthetics to prolong duration of peripheral nerve blocks with minimal side-effects. The present study investigates the efficacy of dexamethasone added to ropivacaine 0.2% as… read more here.
Keywords: ropivacaine; unilateral radical; pecs; radical mastectomy ... See more keywords
Comparison of the onset time between 0.375% ropivacaine and 0.25% levobupivacaine for ultrasound-guided infraclavicular brachial plexus block: a randomized-controlled trial
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-84172-2
Abstract: At centers with pressure on rapid operating room turnover, onset time is one of the important considerations for choosing a local anesthetic drug. To hasten the onset of the block, higher concentrations of local anesthetics… read more here.
Keywords: block; infraclavicular brachial; 375 ropivacaine; brachial plexus ... See more keywords
Preparation and evaluation of liposome with ropivacaine ion-pairing in local pain management
Sign Up to like & getrecommendations! Published in 2022 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2022.2106995
Abstract: Abstract Local analgesia is one of the most desirable methods for postoperative pain control, while the existing local anesthetics have a short duration of analgesic effect. Nano-drug carriers have been widely used in various fields… read more here.
Keywords: ion pairing; local pain; preparation; pain ... See more keywords
Pre-, Peri-, and Postoperative Intravenous Ropivacaine versus that of Lidocaine for Analgesia after Hand-Assisted Laparoscopic Surgery of Left Colon Cancer: A Retrospective Analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Investigative Surgery"
DOI: 10.1080/08941939.2020.1801913
Abstract: Abstract Purposes Pre-, peri-, and postoperative intravenous lidocaine are reported effective in the management of postoperative pain in laparoscopic colorectal surgery but until the time, that of ropivacaine is not tested for the same. The… read more here.
Keywords: pre peri; surgery; ropivacaine; lidocaine ... See more keywords
Dexamethasone and Clonidine, but not Epinephrine, Prolong Duration of Ropivacaine Brachial Plexus Blocks, Cross-Sectional Analysis in Outpatient Surgery Setting
Sign Up to like & getrecommendations! Published in 2017 at "Pain Medicine"
DOI: 10.1093/pm/pnw198
Abstract: Objective The primary aim of this study is to determine the effect of adding dexamethasone, clonidine or both with and without epinephrine to ropivacaine and bupivacaine brachial plexus blocks. Design Observational study of prospectively collected… read more here.
Keywords: block; duration; brachial plexus; ropivacaine ... See more keywords
Local Anesthetic Cardiac Toxicity Is Mediated by Cardiomyocyte Calcium Dynamics
Sign Up to like & getrecommendations! Published in 2022 at "Anesthesiology"
DOI: 10.1097/aln.0000000000004389
Abstract: Background: Long-lasting local anesthetic use for perioperative pain control is limited by possible cardiotoxicity (e.g., arrhythmias and contractile depression), potentially leading to cardiac arrest. Off-target cardiac sodium channel blockade is considered the canonical mechanism behind… read more here.
Keywords: calcium dynamics; calcium; toxicity; cardiotoxicity ... See more keywords