Roquin-dependent gene regulation in immune-mediated diseases and future therapies.
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DOI: 10.1093/intimm/dxac059
Abstract: The RNA-binding proteins Roquin-1/2 and Regnase-1 exert essential regulation by controlling proinflammatory mRNA expression to prevent autoimmune disease. More recently, inhibition of this post-transcriptional gene regulatory program has been demonstrated to enable enhanced anti-tumor responses… read more here.
Keywords: gene regulation; regulation; gene; regulation immune ... See more keywords