LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "ror" as a keyword



Photo from wikipedia

Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride.

Sign Up to like & get
recommendations! Published in 2020 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2020.3385

Abstract: Importance There is ongoing controversy about the adverse events of finasteride, a drug used in the management of alopecia and benign prostatic hyperplasia (BPH). In 2012, reports started emerging on men who had used finasteride… read more here.

Keywords: adverse events; ror; psychological adverse; sensitivity analyses ... See more keywords
Photo by bermixstudio from unsplash

Elucidation of an Allosteric Mode of Action for a Thienopyrazole RORγt Inverse Agonist

Sign Up to like & get
recommendations! Published in 2020 at "Chemmedchem"

DOI: 10.1002/cmdc.202000044

Abstract: The demand for allosteric targeting of nuclear receptors is high, but examples are limited, and structural information is scarce. The retinoic acid‐related orphan receptor gamma t (RORγt) is an important transcriptional regulator for the differentiation… read more here.

Keywords: allosteric mode; elucidation allosteric; ror; thienopyrazole ror ... See more keywords
Photo by ospanali from unsplash

miR‐219a‐5p Regulates Rorβ During Osteoblast Differentiation and in Age‐related Bone Loss

Sign Up to like & get
recommendations! Published in 2019 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.3586

Abstract: Developing novel approaches to treat skeletal disorders requires an understanding of how critical molecular factors regulate osteoblast differentiation and bone remodeling. We have reported that (1) retinoic acid receptor‐related orphan receptor beta (Rorβ) is upregulated… read more here.

Keywords: ror expression; mir 219a; ror; bone ... See more keywords
Photo by aaronlee224 from unsplash

Linc‐ROR regulates apoptosis in esophageal squamous cell carcinoma via modulation of p53 ubiquitination by targeting miR‐204‐5p/MDM2

Sign Up to like & get
recommendations! Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.29139

Abstract: The long intergenic noncoding RNA, regulator of reprogramming (linc‐ROR) has been reported to participate in tumorigenesis, while its functions and fundamental mechanisms in esophageal squamous cell carcinoma (ESCC) remain unclear. In this study, gain‐of‐function assays… read more here.

Keywords: esophageal squamous; ror; linc ror; 204 mdm2 ... See more keywords
Photo by kostiantynvierkieiev from unsplash

Purine Antimetabolites associated Pneumocystis Jiroveci Pneumonia.

Sign Up to like & get
recommendations! Published in 2023 at "Pharmacoepidemiology and drug safety"

DOI: 10.1002/pds.5647

Abstract: PURPOSE To detect the possible safety signal of purine antimetabolites associated with pneumocystis jiroveci pneumonia through disproportionality analysis in the FDA Adverse Event Reporting System (FAERS) Database. METHODS A case/non-case retrospective disproportionality analysis was performed… read more here.

Keywords: antimetabolites associated; associated pneumocystis; ror; pneumocystis jiroveci ... See more keywords

Torsade de pointes associated with chloroquine, hydroxychloroquine, and azithromycin: a retrospective analysis of individual case safety reports from VigiBase

Sign Up to like & get
recommendations! Published in 2021 at "European Journal of Clinical Pharmacology"

DOI: 10.1007/s00228-021-03133-w

Abstract: Purpose To analyze the cases of torsade de pointes (TdP) and related symptoms reported in association with chloroquine (CQ), hydroxychloroquine (HCQ), and azithromycin (AZT) to the World Health Organization (WHO) global database of individual case… read more here.

Keywords: hcq; ror; hcq azt; torsade pointes ... See more keywords

The lncRNA ROR/miR-124-3p/TRAF6 axis regulated the ischaemia reperfusion injury-induced inflammatory response in human cardiac myocytes

Sign Up to like & get
recommendations! Published in 2019 at "Journal of Bioenergetics and Biomembranes"

DOI: 10.1007/s10863-019-09812-9

Abstract: Myocardial ischaemia reperfusion injury (MIRI) is considered the primary cause of death in patients with cardiovascular diseases. Recently, long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) have been found to be involved in the pathogenesis of… read more here.

Keywords: lncrna ror; traf6; ror; cell apoptosis ... See more keywords
Photo by sarahdorweiler from unsplash

Returns to Operating Room After Colon and Rectal Surgery in a Tertiary Care Academic Medical Center: a Valid Measure of Surgical Quality?

Sign Up to like & get
recommendations! Published in 2017 at "Journal of Gastrointestinal Surgery"

DOI: 10.1007/s11605-017-3403-4

Abstract: IntroductionReturns to the operating room (ROR) have been suggested as a marker of surgical quality. Increasingly, quality and value metrics are utilized for reimbursement as well as public reporting to inform health care consumers. We… read more here.

Keywords: quality; surgery; ror; colon rectal ... See more keywords
Photo by malyushev from unsplash

Adenosine A2A receptor modulates neuroimmune function through Th17/retinoid-related orphan receptor gamma t (RORγt) signaling in a BTBR T+ Itpr3tf/J mouse model of autism.

Sign Up to like & get
recommendations! Published in 2017 at "Cellular signalling"

DOI: 10.1016/j.cellsig.2017.04.014

Abstract: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by abnormal social interactions, repetitive behaviors that impair social communication, and circumscribed interests. BTBR T+tf/J (BTBR) inbred mice are generally used as a model for… read more here.

Keywords: adenosine a2a; ror; 17a ror; expression levels ... See more keywords
Photo by nci from unsplash

Generation of RORγt+ Antigen-Specific T Regulatory 17 Cells from Foxp3+ Precursors in Autoimmunity.

Sign Up to like & get
recommendations! Published in 2017 at "Cell reports"

DOI: 10.1016/j.celrep.2017.09.021

Abstract: Th17 cells are potent mediators in autoimmune diseases, and RORγt is required for their development. Recent studies have shown that RORγt+ Treg cells in the gut regulate intestinal inflammation by inhibiting effector T cell function. In… read more here.

Keywords: treg cells; ror treg; ror; antigen specific ... See more keywords
Photo by nci from unsplash

RORα is critical for mTORC1 activity in T cell-mediated colitis.

Sign Up to like & get
recommendations! Published in 2021 at "Cell reports"

DOI: 10.1016/j.celrep.2021.109682

Abstract: Inflammatory bowel disease (IBD) is multi-factorial chronic intestinal inflammation driven by pathogenic T cells, among which a large portion of patients are resistant to current anti-inflammatory regimes. The mechanisms underlying colitis pathogenicity and drug resistance are… read more here.

Keywords: mediated colitis; cell mediated; ror; mtorc1 ... See more keywords