First report of ROR2 directed therapy with a conditionally active antibody drug conjugate in advanced melanoma.
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DOI: 10.1200/jco.2025.43.16_suppl.3077
Abstract: 3077 Background: The receptor tyrosine-kinase like orphan receptors (ROR) are mediators of noncanonical WNT signaling and tissue patterning. ROR2 upregulation is observed in malignancy and has been implicated in metastasis. Development of ROR2 directed conditionally… read more here.
Keywords: report; ror2; ror2 directed; drug ... See more keywords