Nicotinamide (niacin) supplement increases lipid metabolism and ROS‐induced energy disruption in triple‐negative breast cancer: potential for drug repositioning as an anti‐tumor agent
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13209
Abstract: Metabolic dysregulation is an important hallmark of cancer. Nicotinamide (NAM), a water‐soluble amide form of niacin (vitamin B3), is currently available as a supplement for maintaining general physiologic functions. NAM is a crucial regulator of… read more here.
Keywords: metabolism; supplement; triple negative; ros ... See more keywords
Engineered Bio‐Heterojunction with Robust ROS‐Scavenging and Anti‐Inflammation for Targeted Acute Pancreatitis Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202413276
Abstract: Acute pancreatitis (AP) is one of the most severe mortal inflammatory diseases worldwide, which is characterized by the over‐activation of reactive oxygen species (ROS)‐induced inflammation and pancreatic enzymes (PEs). As the PEs induced by ROS… read more here.
Keywords: ros; engineered bio; bio hjs; ros scavenging ... See more keywords
Carbon Dots in the Pathological Microenvironment: ROS Producers or Scavengers?
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202402108
Abstract: Reactive oxygen species (ROS), as metabolic byproducts, play pivotal role in physiological and pathological processes. Recently, studies on the regulation of ROS levels for disease treatments have attracted extensive attention, mainly involving the ROS‐induced toxicity… read more here.
Keywords: ros; ros producers; carbon dots; ros modulating ... See more keywords
Engineered Apoptotic Extracellular Vesicles for Programmable Regulation of Neutrophil-Macrophage-ROS Pathogenic Axis to Reconstruct Rheumatoid Arthritis Microenvironment.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced materials"
DOI: 10.1002/adma.202508072
Abstract: Rheumatoid arthritis microenvironment (RAM) contains complex pathogenic mediators that interact dynamically to drive the progression of rheumatoid arthritis (RA). However, most current RA treatments are single‐target interventions, exerting limited impact on RAM. Herein, apoptotic extracellular… read more here.
Keywords: ros; arthritis microenvironment; rheumatoid; rheumatoid arthritis ... See more keywords
An Intelligent and Conductive Hydrogel with Multiresponsive and ROS Scavenging Properties for Infection Prevention and Anti‐Inflammatory Treatment Assisted by Electrical Stimulation for Diabetic Wound
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202500696
Abstract: Diabetic wounds experience a hyperglycemic, hypoxic environment, combined with ongoing oxidative stress and inflammatory imbalances, significantly disrupts normal healing process. Advanced hydrogels have been considered one of the most exciting medical biomaterials for the potential… read more here.
Keywords: ros; conductive hydrogel; electrical stimulation; intelligent conductive ... See more keywords
N‐Acety‐L‐Cysteine Alleviates Isoflurane‐Triggered Neuronal Cell Parthanatos by Suppressing Reactive Oxygen Species Accumulation Through the Induction of c‐Jun N‐Terminal Kinase Signaling Pathway Inhibition
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.70268
Abstract: In recent years, the potential neurotoxicity of inhaled anesthetics on the developing brain has increasingly garnered attention, yet its mechanism remains unclear. Parthanatos is a newly discovered form of programmed cell death dependent on PARP‐1,… read more here.
Keywords: ros; isoflurane; oxidative stress; cell ... See more keywords
Markers for Mitochondrial ROS Status.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1653-6_15
Abstract: Mitochondria actively participate in oxygenic metabolism and are one of the major sources of reactive oxygen species (ROS) production in plant cells. However, instead of measuring ROS concentrations in organelles it is more worthwhile to… read more here.
Keywords: mitochondrial ros; production; ros; ros status ... See more keywords
Cellular and Molecular Processes in Pulmonary Hypertension.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-68748-9_2
Abstract: Pulmonary hypertension (PH) is a progressive lung disease characterized by persistent pulmonary vasoconstriction. Another well-recognized characteristic of PH is the muscularization of peripheral pulmonary arteries. This pulmonary vasoremodeling manifests in medial hypertrophy/hyperplasia of smooth muscle… read more here.
Keywords: pulmonary hypertension; ros; processes pulmonary; molecular processes ... See more keywords
Signal Function Studies of ROS, Especially RBOH-Dependent ROS, in Plant Growth, Development and Environmental Stress
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Plant Growth Regulation"
DOI: 10.1007/s00344-019-09971-4
Abstract: Reactive oxygen species (ROS) are well known for their dual functions in plants. On the one hand, ROS were once thought to be harmful to plants because their excessive accumulation might lead to oxidative stress… read more here.
Keywords: plant growth; ros; plant; growth development ... See more keywords
ROS induced bactericidal activity of amorphous Zn-doped titanium oxide coatings and enhanced osseointegration in bacteria-infected rat tibias.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.02.036
Abstract: Titanium-based endosseous implants with high antibacterial and osseointegration activities are extremely required in clinics. To achieve this line, herein the doped coatings with three kinds of Zn doses were micro-arc oxidized (MAOed) on Ti. They… read more here.
Keywords: infected rat; ros; coatings enhanced; titanium ... See more keywords
The β2-adrenergic receptor-ROS signaling axis: an overlooked component of β2AR function?
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2019.113690
Abstract: β2-adrenergic receptor (β2AR) agonists are clinically used to elicit rapid bronchodilation for the treatment of bronchospasms in pulmonary diseases such as asthma and COPD, both of which exhibit characteristically high levels of reactive oxygen species… read more here.
Keywords: axis; adrenergic receptor; ros; 2ar function ... See more keywords