Carnosic acid (CA) attenuates collagen‐induced arthritis in db/db mice via inflammation suppression by regulating ROS‐dependent p38 pathway
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.03.023
Abstract: Abstract Rheumatoid arthritis (RA) is a multifactorial autoimmune disease, characterized by inflammation of synovial joints. Carnosic acid (CA) is a phenolic diterpene isolated from Rosmarinus officinailis, playing a central role in cytoprotective responses to oxidative… read more here.
Keywords: dependent p38; inflammation; ros dependent; acid ... See more keywords
Anticancer effect of Polyphyllin Ι in colorectal cancer cells through ROS-dependent autophagy and G2/M arrest mechanisms
Sign Up to like & getrecommendations! Published in 2018 at "Natural Product Research"
DOI: 10.1080/14786419.2017.1353512
Abstract: Abstract Polyphyllin Ι is a steroidal saponin isolated from the rhizoma of Paris polyphylla. In the present study, we aimed to investigate the anticancer effects of polyphyllin Ι in colorectal cancer and to elucidate the… read more here.
Keywords: colorectal cancer; ros dependent; anticancer; polyphyllin ... See more keywords
Proteome-wide analysis reveals molecular pathways affected by AgNP in a ROS-dependent manner
Sign Up to like & getrecommendations! Published in 2022 at "Nanotoxicology"
DOI: 10.1080/17435390.2022.2036844
Abstract: Abstract The use of mass spectrometry-based proteomics has been increasingly applied in nanomaterials risk assessments as it provides a proteome-wide overview of the molecular disturbances induced by its exposure. Here, we used this technique to… read more here.
Keywords: pathways affected; affected agnp; ros dependent; dependent manner ... See more keywords
Mycoplasma ovipneumoniae induces caspase-8-dependent extrinsic apoptosis and p53- and ROS-dependent intrinsic apoptosis in murine alveolar macrophages.
Sign Up to like & getrecommendations! Published in 2021 at "Virulence"
DOI: 10.1080/21505594.2021.1984714
Abstract: Mycoplasma ovipneumoniae (MO) is a principle causative agent of chronic respiratory disease in ruminants, including sheep, goats, and deer, posing a great threat to the ruminant industry worldwide. However, the pathogenesis of MO infection still… read more here.
Keywords: apoptosis; infection; ros dependent; mycoplasma ovipneumoniae ... See more keywords
Celastrol ameliorates Cd‐induced neuronal apoptosis by targeting NOX2‐derived ROS‐dependent PP5‐JNK signaling pathway
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.13966
Abstract: Celastrol, a plant‐derived triterpene, has neuroprotective benefit in the models of neurodegenerative disorders that are characterized by overproduction of reactive oxygen species (ROS). Recently, we have reported that cadmium (Cd) activates c‐Jun N‐terminal kinase (JNK)… read more here.
Keywords: jnk; pp5; neuronal apoptosis; ros dependent ... See more keywords
Increased ROS-Dependent Fission of Mitochondria Causes Abnormal Morphology of the Cell Powerhouses in a Murine Model of Amyotrophic Lateral Sclerosis
Sign Up to like & getrecommendations! Published in 2021 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2021/6924251
Abstract: Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease in humans and remains to have a fatal prognosis. Recent studies in animal models and human ALS patients indicate that increased reactive oxygen species… read more here.
Keywords: ros dependent; mitochondria; amyotrophic lateral; increased ros ... See more keywords
Nanoscale Features of Gambogic Acid Induced ROS-Dependent Apoptosis in Esophageal Cancer Cells Imaged by Atomic Force Microscopy
Sign Up to like & getrecommendations! Published in 2022 at "Scanning"
DOI: 10.1155/2022/1422185
Abstract: Gambogic acid (GA), a kind of polyprenylated xanthone derived from Garcinia hanburyi tree, has showed spectrum anticancer effects both in vitro and in vivo with low toxicity. However, up to now, there is little information… read more here.
Keywords: esophageal cancer; anticancer effects; microscopy; gambogic acid ... See more keywords
Type 2 Diabetes Promotes Cell Centrosome Amplification via AKT-ROS-Dependent Signalling of ROCK1 and 14-3-3σ
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000489812
Abstract: Background/Aims: Type 2 diabetes is associated with oxidative stress and DNA damage which can cause centrosome amplification. Thus, the study investigated centrosome amplification in type 2 diabetes and the underlying mechanisms. Methods: Centrosome numbers in… read more here.
Keywords: akt ros; ros dependent; type diabetes; centrosome amplification ... See more keywords
Cytotoxicity Mechanisms of Blue-Light-Activated Curcumin in T98G Cell Line: Inducing Apoptosis through ROS-Dependent Downregulation of MMP Pathways
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043842
Abstract: We examined the photodynamic activation of Curcumin under blue light in glioblastoma T98G cells. The therapeutic effect of Curcumin, in both the absence and presence of blue light, was measured by the MTT assay and… read more here.
Keywords: apoptosis; t98g; curcumin; blue light ... See more keywords
Scopoletin protects retinal ganglion cells 5 from high glucose-induced injury in a cellular model of diabetic retinopathy via ROS-dependent p38 and JNK signaling cascade
Sign Up to like & getrecommendations! Published in 2022 at "Central-European Journal of Immunology"
DOI: 10.5114/ceji.2022.115710
Abstract: The protective activity of scopoletin (SPT) against glucose-induced cataract has been attributed to attenuation of aldose reductase activity and oxidative stress in a rat model. The present investigation was aimed to study the protective effect… read more here.
Keywords: rgc cells; p38 jnk; glucose induced; dependent p38 ... See more keywords