MicroRNA‐1225 activates Keap1‐Nrf2‐HO‐1 signalling to inhibit TNFα‐induced osteoclastogenesis by mediating ROS generation
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3394
Abstract: The influence of miRNA‐1225‐5p (miR‐1225) and Keap1‐Nrf2 signalling on in vitro osteoclast differentiation in mouse models was studied along with the underlying mechanism. In differentiated bone marrow–derived macrophages (BMMs), downregulated miR‐1225 and upregulated Keap1 were… read more here.
Keywords: mir 1225; tnf; keap1 nrf2; ros generation ... See more keywords
Manipulation of Actin Cytoskeleton by Intracellular-Targeted ROS Generation.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1258-3_23
Abstract: A method to generate small amount of reactive oxygen species (ROSs) at intracellular targeted region has great potential to manipulate the function of particular proteins. The present protocol introduces a fusion protein that consisted of firefly… read more here.
Keywords: actin cytoskeleton; cytoskeleton intracellular; ros generation; manipulation actin ... See more keywords
PGC-1α protects against oxidized low-density lipoprotein and luteinizing hormone-induced granulosa cells injury through ROS-p38 pathway
Sign Up to like & getrecommendations! Published in 2019 at "Human Cell"
DOI: 10.1007/s13577-019-00252-6
Abstract: Obese women with polycystic ovary syndrome (PCOS) often suffer from ovulation failure, which may be driven by granulosa cells (GCs) injury caused by increased levels of circulating oxidized low-density lipoprotein (ox-LDL) and luteinizing hormone (LH).… read more here.
Keywords: ros generation; injury; pgc; pcos group ... See more keywords
Non-thermal plasma induces mitochondria-mediated apoptotic signaling pathway via ROS generation in HeLa cells.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2017.09.005
Abstract: Non-thermal plasma (NTP) has been proposed as a novel therapeutic method for anticancer treatment. Although increasing evidence suggests that NTP selectively induces apoptosis in some types of tumor cells, the molecular mechanisms underlying this phenomenon… read more here.
Keywords: mitochondria mediated; ros generation; hela; ntp exposure ... See more keywords
The reactive oxygen species as pathogenic factors of fragmented microplastics to macrophages.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.117006
Abstract: The presence of microplastics in the various food web raised concerns on human health, but little is known about the target cells and mechanism of toxicity of microplastics. In this study, we evaluated the toxicity… read more here.
Keywords: reactive oxygen; oxygen species; toxicity; ros generation ... See more keywords
In situ electrochemical monitoring of ROS influence in the dynamics of ascorbic acid and polyphenolic compounds in apple fruits.
Sign Up to like & getrecommendations! Published in 2021 at "Food chemistry"
DOI: 10.1016/j.foodchem.2021.131818
Abstract: In situ recording of the voltammetric profile of different apple (Malus domestica Borkh.) varieties (Golden, Granny Smith, Reineta, Red delicious, Fuji, and Braeburn) without and with ROS generation is reported. The voltammetric response associated to… read more here.
Keywords: electrochemical monitoring; apple; ascorbic acid; situ electrochemical ... See more keywords
Damage of cystatin due to ROS-generation and radical-scavenging activity of antioxidants and associated compounds.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.07.100
Abstract: Cystatins are thiol proteinase inhibitors present ubiquitously in mammalian system. They prevent unwanted proteolysis and are involved in several neurodegenerative diseases. Hydrogen peroxide, hydroxyl radical and superoxide radical were produced during the autoxidation of various… read more here.
Keywords: cystatin; damage cystatin; ros generation; due ros ... See more keywords
Triolein reduces MMP-1 upregulation in dermal fibroblasts generated by ROS production in UVB-irradiated keratinocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2016.11.010
Abstract: BACKGROUND Cytokine production and oxidative stress generated by ultraviolet radiation B (UVB) skin exposure are main factors of skin photoaging. Interleukin-6 (IL-6) produced by irradiated keratinocytes is proposed to have a role in metalloproteinases (MMPs)… read more here.
Keywords: expression ros; irradiated keratinocytes; ros generation; expression ... See more keywords
Enhanced ROS generation by ZnO-ammonia modified graphene oxide nanocomposites for photocatalytic degradation of trypan blue dye and 4-nitrophenol
Sign Up to like & getrecommendations! Published in 2017 at "Journal of environmental chemical engineering"
DOI: 10.1016/j.jece.2017.08.026
Abstract: Abstract There has been consistent effort on manipulating surface properties of ZnO NPs to produce higher concentration of reactive oxygen species (ROS) to enhance sustained photocatalytic degradation. Here we present a very simple strategy of… read more here.
Keywords: graphene oxide; degradation; ros generation; dye ... See more keywords
RNF34 ablation promotes cerebrovascular remodeling and hypertension by increasing NADPH-derived ROS generation
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2021.105396
Abstract: Cerebrovascular remodeling is the most common cause of hypertension and stroke. Ubiquitin E3 ligase RING finger protein 34 (RNF34) is suggested to be associated with the development of multiple neurological diseases. However, the importance of… read more here.
Keywords: remodeling hypertension; rnf34; ros generation; derived ros ... See more keywords
The involvement of ROS generation on Epoxiconazole-induced toxicity in HCT116 cells.
Sign Up to like & getrecommendations! Published in 2018 at "Pesticide biochemistry and physiology"
DOI: 10.1016/j.pestbp.2018.03.014
Abstract: Abstract Triazole fungicides are the most efficient class of pesticides and have been in rapid development since the 1970s, receiving worldwide recognition. Epoxiconazole is a systemic fungicide belonging to the most widely used members of… read more here.
Keywords: involvement ros; generation; ros generation; generation epoxiconazole ... See more keywords