Abstract 5853: Peroxiredoxin I-targeted AMRI-59 has a role of radiosensitizer by promoting induction of ROS/γH2AX/caspase pathway and suppression of ERK
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DOI: 10.1158/1538-7445.am2017-5853
Abstract: We have identified AMRI-59, one of small molecule, is specific pharmaceutical inhibitor of peroxiredoxin (PRX) I enzyme activity in our previous study. In this study, we tried to prove whether AMRI-59 has role of radiosensitizer… read more here.
Keywords: suppression; amri role; role radiosensitizer; ros h2ax ... See more keywords