APC/C CDH1 ubiquitinates IDH2 contributing to ROS increase in mitosis.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2021.110087
Abstract: NADPH is a cofactor used by reactive oxygen species (ROS) scavenging enzymes to block ROS produced in cells. Recently, it was shown that in cancer cells, ROS progressively increases in tune to cell cycle leading… read more here.
Keywords: cdh1; mitosis; ros increase; apc cdh1 ... See more keywords
ROS Increase Chemo-reagent Concentration by the Down Regulation of BCRP During Both Hyperthermia and Chemotherapy
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.10.138
Abstract: Hyperthermia (HT) is a non-invasive cancer therapy. Treatment temperature between 41 to 44°C has no cytotoxic damage in normal cells, while the temperature does in cancer cells because of the underdeveloped vascular system. HT often… read more here.
Keywords: chemotherapy; bcrp; ros increase; treatment ... See more keywords
TPP-Based Nanovesicles Kill MDR Neuroblastoma Cells and Induce Moderate ROS Increase, While Exerting Low Toxicity Towards Primary Cell Cultures: An In Vitro Study
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26114991
Abstract: Neuroblastoma (NB) is a malignant childhood tumour, which originates from neuroblasts with an incidence of approximately 15,000 new cases per year worldwide. Therapy-induced secondary tumorigenesis and the emergency of drug resistance in its high-risk (HR-NB)… read more here.
Keywords: primary cell; ros increase; bppb; cell ... See more keywords