Carbon Dots in the Pathological Microenvironment: ROS Producers or Scavengers?
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202402108
Abstract: Reactive oxygen species (ROS), as metabolic byproducts, play pivotal role in physiological and pathological processes. Recently, studies on the regulation of ROS levels for disease treatments have attracted extensive attention, mainly involving the ROS‐induced toxicity… read more here.
Keywords: ros; ros producers; carbon dots; ros modulating ... See more keywords
Discovery of an 8-oxoguanine regulator PCBP1 inhibitor by virtual screening and its synergistic effects with ROS-modulating agents in pancreatic cancer
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2024.1441550
Abstract: Introduction: Drugs that target reactive oxygen species (ROS) metabolism have progressed the treatment of pancreatic cancer treatment, yet their efficacy remains poor because of the adaptation of cancer cells to high concentration of ROS. Cells… read more here.
Keywords: cancer; virtual screening; pcbp1; ros modulating ... See more keywords
ROS Modulating Effects of Lingonberry (Vaccinium vitis-idaea L.) Polyphenols on Obese Adipocyte Hypertrophy and Vascular Endothelial Dysfunction
Sign Up to like & getrecommendations! Published in 2021 at "Nutrients"
DOI: 10.3390/nu13030885
Abstract: Oxidative stress and dysregulated adipocytokine secretion accompanying hypertrophied adipose tissue induce chronic inflammation, which leads to vascular endothelial dysfunction. The present study investigated the ability of anthocyanin (ACN) and non-anthocyanin polyphenol (PP) fractions from lingonberry… read more here.
Keywords: vascular endothelial; dysfunction; hypertrophy; expression ... See more keywords