Mitochondrial ROS overproduction impairs glutamatergic signaling in frontotemporal dementia
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DOI: 10.1016/j.freeradbiomed.2018.04.207
Abstract: Glutamatergic neurotransmission is essential for learning and memory but an overactivation of the pathway may lead to calcium overload, excitotoxicity and neuronal death. Together with this, oxidative stress and mitochondrial dysfunction are all relevant to… read more here.
Keywords: mitochondrial ros; frontotemporal dementia; ros; ros overproduction ... See more keywords