H3 relaxin inhibits the collagen synthesis via ROS‐ and P2X7R‐mediated NLRP3 inflammasome activation in cardiac fibroblasts under high glucose
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DOI: 10.1111/jcmm.13464
Abstract: Excessive production of reactive oxygen species (ROS) and P2X7R activation induced by high glucose increases NLRP3 inflammasome activation, which contributes to the pathogenesis of diabetic cardiomyopathy. Although H3 relaxin has been shown to inhibit cardiac… read more here.
Keywords: collagen synthesis; ros p2x7r; activation; nlrp3 inflammasome ... See more keywords