Pravastatin alleviates intracellular calcium dysregulation induced by Interleukin-6 via the mitochondrial ROS pathway in adult ventricular myocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2020.01.013
Abstract: Acute inflammation often contributes to the increased arrhythmogenesis in the cardiomyocytes. We investigated the protective effects of pravastatin on calcium disorders induced by acute administration of pro-inflammatory cytokines in isolated ventricular myocytes and its underlying… read more here.
Keywords: ros pathway; mitochondrial ros; ventricular myocytes; ca2 ... See more keywords
Sesamin Protects Against Cardiac Remodeling Via Sirt3/ROS Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000486026
Abstract: Background/Aims: Cardiac remodeling is associated with oxidative stress. Sesamin, a well-known antioxidant from sesamin seeds, have been used extensively as traditional health foods. However, there is little known about the effect of sesamin on cardiac… read more here.
Keywords: ros pathway; sirt3 ros; sesamin; via sirt3 ... See more keywords
Dihydromyricetin functions as a tumor suppressor in hepatoblastoma by regulating SOD1/ROS pathway
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1160548
Abstract: Background Hepatoblastoma has an unsatisfactory prognosis, and traditional chemotherapy has strong side effects. Dihydromyricetin is a flavonoid extracted from a woody vine of the genus Serpentine in the family Vitaceae, with effects such as preventing… read more here.
Keywords: sod1 ros; tumor suppressor; hepatoblastoma; dhm ... See more keywords