VEGF‐A promotes angiogenesis after acute myocardial infarction through increasing ROS production and enhancing ER stress‐mediated autophagy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28395
Abstract: Proangiogenesis is generally regarded as an effective approach for treating ischemic heart disease. Vascular endothelial growth factor (VEGF)‐A is a strong and essential proangiogenic factor. Reactive oxygen species (ROS), endoplasmic reticulum (ER) stress, and autophagy… read more here.
Keywords: lc3; production; vegf; grp78 bip ... See more keywords
Hv1/VSOP regulates neutrophil directional migration and ERK activity by tuning ROS production
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.2a0320-110rr
Abstract: High‐level reactive oxygen species (ROS) production in neutrophils is tightly regulated, as it can damage host cells. Neutrophils also undergo low‐level ROS production when stimulated by cytokines or chemoattractants, but its biologic significance remains largely… read more here.
Keywords: production; hv1 vsop; directional migration; ros production ... See more keywords
Revealing ROS Production by Antibiotics and Photosensitizers in Biofilms: A Fluorescence Microscopy Approach.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0896-8_11
Abstract: Reactive oxygen species (ROS) production within biofilms is studied with a simple and easy setup based on fluorescence microscopy. Herein, a biofilm is exposed to different ROS inducers: a bactericidal antibiotic (ciprofloxacin) and a BODIPY-based… read more here.
Keywords: ros production; fluorescence microscopy; revealing ros; microscopy ... See more keywords
Assessment of ROS Production in the Mitochondria of Live Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0896-8_2
Abstract: Production of reactive oxygen species (ROS) in the mitochondria plays multiple roles in physiology, and excessive production of ROS leads to the development of various pathologies. ROS in the mitochondria are generated by various enzymes,… read more here.
Keywords: production; mitochondria live; live cells; ros production ... See more keywords
Modelling mitochondrial ROS production by the respiratory chain
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03381-1
Abstract: ROS (superoxide and oxygen peroxide in this paper) play a dual role as signalling molecules and strong oxidizing agents leading to oxidative stress. Their production mainly occurs in mitochondria although they may have other locations… read more here.
Keywords: ros production; respiratory chain; production; mitochondrial ros ... See more keywords
Mitochondrial NADH redox potential impacts the reactive oxygen species production of reverse Electron transfer through complex I
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-018-9767-7
Abstract: There is substantial evidence that Reactive Oxygen Species (ROS) play a major part in cell functioning. Although their harmfulness through oxidative stress is well documented, their role in signaling and sensing as an oxidative signal… read more here.
Keywords: electron transfer; ros production; reverse electron; production ... See more keywords
Effects of Copper on Hemocyte Apoptosis, ROS Production, and Gene Expression in White Shrimp Litopenaeus vannamei
Sign Up to like & getrecommendations! Published in 2017 at "Biological Trace Element Research"
DOI: 10.1007/s12011-017-0974-6
Abstract: Copper, a common chemical contaminant in aquatic environment, is known to be toxic to aquatic life at high concentrations. In the present study, we evaluated the apoptotic cell ratio and ROS production in hemocytes of… read more here.
Keywords: apoptosis; ros production; expression; shrimp ... See more keywords
GCN2 suppression attenuates cerebral ischemia in mice by reducing apoptosis and endoplasmic reticulum (ER) stress through the blockage of FoxO3a-regulated ROS production.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.05.181
Abstract: Ischemic stroke is one of the leading causes of morbidity and mortality among human worldwide. Unfortunately, cerebral I/R still lacks effective therapeutic targets and strategies. In the study, we found that general control nonderepressible 2… read more here.
Keywords: suppression; gcn2 suppression; ros production; stress ... See more keywords
Class I phosphoinositide 3-kinases control sustained NADPH oxidase activation in adherent neutrophils.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.114088
Abstract: Phagocytes, especially neutrophils, can produce reactive oxygen species (ROS), through the activation of the NADPH oxidase (NOX2). Although this enzyme is crucial for host-pathogen defense, ROS production by neutrophils can be harmful in several pathologies… read more here.
Keywords: class; ros production; oxidase activation; activation ... See more keywords
The new mitochondrial uncoupler BAM15 induces ROS production for treatment of acute myeloid leukemia.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2022.114948
Abstract: Acute myeloid leukemia (AML) is a malignant proliferative disease of myeloid hematopoietic origin and cannot be treated appropriately at present. This is due to the fact that leukemia cells are not sensitive to some of… read more here.
Keywords: ros production; acute myeloid; bam15; myeloid leukemia ... See more keywords
Dysregulation of Mitochondrial Permeability Transition Pore (MPTP) is Associated with Enhanced ROS Production in Skeletal Muscle of an ALS Mouse Model
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1759
Abstract: Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disease. Oxidative stress is implicated in ALS pathophysiology. Using ROS Brite™ 570, a cytosolic ROS detector, we found a significant increase in ROS production of muscle fibers… read more here.
Keywords: mptp; mitochondrial permeability; muscle; ros production ... See more keywords