Sponge‐Like Macroporous Hydrogel with Antibacterial and ROS Scavenging Capabilities for Diabetic Wound Regeneration (Adv. Healthcare Mater. 20/2022)
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200717
Abstract: Hydrogels with soft and wet properties have been intensively investigated for chronic disease tissue repair. Nevertheless, tissue engineering hydrogels containing high water content are often simultaneously suffered from low porous size and low water-resistant capacities,… read more here.
Keywords: sponge like; water; ros scavenging; macro porous ... See more keywords
Small Ceria Nanoclusters with High ROS Scavenging Activity and Favorable Pharmacokinetic Parameters for the Amelioration of Chronic Kidney Disease.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300632
Abstract: The over production of reactive oxygen species (ROS) plays a critical role in the progression of chronic kidney disease (CKD). Organic ROS scavengers currently used for CKD treatment do not satisfy low dosage and high… read more here.
Keywords: chronic kidney; scavenging activity; ros scavenging; ceria ... See more keywords
Bioceramic Scaffolds with Antioxidative Functions for ROS Scavenging and Osteochondral Regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202105727
Abstract: Osteoarthritis (OA) is a degenerative disease that involves excess reactive oxygen species (ROS) and osteochondral defects. Although multiple approaches have been developed for osteochondral regeneration, how to balance the biochemical and physical microenvironment in OA… read more here.
Keywords: regeneration; scaffolds antioxidative; ros scavenging; scavenging osteochondral ... See more keywords
Thrombus Inhibition and Neuroprotection for Ischemic Stroke Treatment through Platelet Regulation and ROS Scavenging
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200317
Abstract: Ischemic stroke is caused by cerebrovascular stenosis or occlusion. Excessive reactive oxygen species (ROS) are the focus‐triggering factor of irreversible injury in ischemic regions, which result in harmful cascading effects to brain tissue, such as… read more here.
Keywords: thrombus inhibition; ros scavenging; brain; stroke ... See more keywords
Self-Propelled Ultrasmall AuNPs-Tannic Acid Hybrid Nanozyme with ROS-Scavenging and Anti-Inflammatory Activity for Drug-Induced Liver Injury Alleviation.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202206408
Abstract: Developing nanomedicines with superior reactive oxygen species (ROS) scavenging capability has emerged as a promising strategy in treating ROS-related diseases, for example, drug-induced liver injury. However, designing nanoscavengers with the self-propelling ability to scavenge ROS… read more here.
Keywords: drug induced; liver injury; ros scavenging; induced liver ... See more keywords
ROS-scavenging hydrogel to promote healing of bacteria infected diabetic wounds.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120286
Abstract: Bacterial infection has been a great threat to dermal wounds, especially to difficult-to-heal diabetic wounds. It is known that reactive oxygen species (ROS) generated by wounds or bacterial infection could further impede wound healing. Here,… read more here.
Keywords: bacterial infection; hydrogel; diabetic wounds; scavenging hydrogel ... See more keywords
ROS-Scavenging Therapeutic Hydrogels for Modulation of the Inflammatory Response.
Sign Up to like & getrecommendations! Published in 2021 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c18261
Abstract: Although reactive oxygen species (ROS) are essential for cellular processes, excessive ROS could be a major cause of various inflammatory diseases because of the oxidation of proteins, DNA, and membrane lipids. It has recently been… read more here.
Keywords: scavenging hydrogels; ros scavenging; inflammatory; hydrogels modulation ... See more keywords
ROS-Scavenging Selenofluoxetine Derivatives Inhibit In Vivo Serotonin Reuptake
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c05567
Abstract: While the neurochemistry that underpins the behavioral phenotypes of depression is the subject of many studies, oxidative stress caused by the inflammation comorbid with depression has not adequately been addressed. In this study, we described… read more here.
Keywords: selenofluoxetine derivatives; ros scavenging; derivatives inhibit; inhibit vivo ... See more keywords
1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2020.1748026
Abstract: Abstract There are numerous studies supporting the contribution of oxidative stress to the pathogenesis of epilepsy. Prolonged oxidative stress is associated with the overexpression of ATP-binding cassette transporters, which results in antiepileptic drugs resistance. During… read more here.
Keywords: epilepsy; pharmacoresistant epilepsy; ros scavenging; model pharmacoresistant ... See more keywords
Stem cell spheroid engineering with osteoinductive and ROS scavenging nanofibers for bone regeneration
Sign Up to like & getrecommendations! Published in 2020 at "Biofabrication"
DOI: 10.1088/1758-5090/abd56c
Abstract: Stem cell spheroids have been widely investigated to accelerate bone tissue regeneration. However, the directed differentiation of stem cells into osteoblastic lineage and the prevention of cells from damage by reactive oxygen species (ROS) remain… read more here.
Keywords: regeneration; osteoinductive ros; stem cell; ros scavenging ... See more keywords
Astragaloside IV Attenuates Myocardial Ischemia-Reperfusion Injury from Oxidative Stress by Regulating Succinate, Lysophospholipid Metabolism, and ROS Scavenging System
Sign Up to like & getrecommendations! Published in 2019 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2019/9137654
Abstract: Astragaloside IV is one of the main active ingredients isolated from Astragalus membranaceus. Here we confirmed its protective effect against cardiac ischemia-reperfusion (I/R) injury and aimed to investigate the potential molecular mechanisms involved. Pretreatment of… read more here.
Keywords: ros scavenging; succinate; ischemia reperfusion; reperfusion injury ... See more keywords