Engineered Bio‐Heterojunction with Robust ROS‐Scavenging and Anti‐Inflammation for Targeted Acute Pancreatitis Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202413276
Abstract: Acute pancreatitis (AP) is one of the most severe mortal inflammatory diseases worldwide, which is characterized by the over‐activation of reactive oxygen species (ROS)‐induced inflammation and pancreatic enzymes (PEs). As the PEs induced by ROS… read more here.
Keywords: ros; engineered bio; bio hjs; ros scavenging ... See more keywords
Sponge‐Like Macroporous Hydrogel with Antibacterial and ROS Scavenging Capabilities for Diabetic Wound Regeneration (Adv. Healthcare Mater. 20/2022)
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200717
Abstract: Hydrogels with soft and wet properties have been intensively investigated for chronic disease tissue repair. Nevertheless, tissue engineering hydrogels containing high water content are often simultaneously suffered from low porous size and low water-resistant capacities,… read more here.
Keywords: sponge like; water; ros scavenging; macro porous ... See more keywords
Small Ceria Nanoclusters with High ROS Scavenging Activity and Favorable Pharmacokinetic Parameters for the Amelioration of Chronic Kidney Disease.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300632
Abstract: The over production of reactive oxygen species (ROS) plays a critical role in the progression of chronic kidney disease (CKD). Organic ROS scavengers currently used for CKD treatment do not satisfy low dosage and high… read more here.
Keywords: chronic kidney; scavenging activity; ros scavenging; ceria ... See more keywords
Targeted ROS Scavenging for Disease Therapies Using Nanomaterials.
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DOI: 10.1002/adma.202504435
Abstract: Reactive oxygen species (ROS) are essential by‐products of cellular metabolism and serve as key mediators in cell signaling and homeostasis. Excessive ROS production is associated with cellular damage and various diseases. Therefore, targeted ROS scavenging… read more here.
Keywords: nanomaterials targeted; scavenging disease; targeted ros; ros scavenging ... See more keywords
Iron‐Chelating and ROS‐Scavenging Polymers with Thioketal and Thioether Bonds Delivering Ferroptosis Inhibitor Lip‐1 Provide a Triple Therapeutic Strategy for Retina Ganglion Cells in Acute Glaucoma
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Materials"
DOI: 10.1002/adma.202507526
Abstract: Glaucoma is an irreversible blinding eye disease characterized by retinal ganglion cell (RGC) death with emerging evidence highlighting ferroptosis as a crucial mechanism. Herein, two iron‐chelating and reactive oxygen species (ROS)‐scavenging polymers with thioketal and… read more here.
Keywords: iron chelating; lip; glaucoma; ferroptosis ... See more keywords
Bioceramic Scaffolds with Antioxidative Functions for ROS Scavenging and Osteochondral Regeneration
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DOI: 10.1002/advs.202105727
Abstract: Osteoarthritis (OA) is a degenerative disease that involves excess reactive oxygen species (ROS) and osteochondral defects. Although multiple approaches have been developed for osteochondral regeneration, how to balance the biochemical and physical microenvironment in OA… read more here.
Keywords: regeneration; scaffolds antioxidative; ros scavenging; scavenging osteochondral ... See more keywords
Thrombus Inhibition and Neuroprotection for Ischemic Stroke Treatment through Platelet Regulation and ROS Scavenging
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DOI: 10.1002/cmdc.202200317
Abstract: Ischemic stroke is caused by cerebrovascular stenosis or occlusion. Excessive reactive oxygen species (ROS) are the focus‐triggering factor of irreversible injury in ischemic regions, which result in harmful cascading effects to brain tissue, such as… read more here.
Keywords: thrombus inhibition; ros scavenging; brain; stroke ... See more keywords
Self-Propelled Ultrasmall AuNPs-Tannic Acid Hybrid Nanozyme with ROS-Scavenging and Anti-Inflammatory Activity for Drug-Induced Liver Injury Alleviation.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202206408
Abstract: Developing nanomedicines with superior reactive oxygen species (ROS) scavenging capability has emerged as a promising strategy in treating ROS-related diseases, for example, drug-induced liver injury. However, designing nanoscavengers with the self-propelling ability to scavenge ROS… read more here.
Keywords: drug induced; liver injury; ros scavenging; induced liver ... See more keywords
A Factor-Free Hydrogel with ROS Scavenging and Responsive Degradation for Enhanced Diabetic Bone Healing.
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DOI: 10.1002/smll.202306389
Abstract: In view of the increased levels of reactive oxygen species (ROS) that disturb the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs), the repair of diabetic bone defects remains a great challenge. Herein, a… read more here.
Keywords: bone; responsive degradation; ros scavenging; diabetic bone ... See more keywords
Ta4C3 Nanosheets as a Novel Therapeutic Platform for Photothermal-Driven ROS Scavenging and Immune Activation against Antibiotic-Resistant Infections in Diabetic Wounds.
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DOI: 10.1002/smll.202400741
Abstract: The accumulation of excessive reactive oxygen species (ROS) and recurrent infections with drug-resistant bacteria pose significant challenges in diabetic wound infections, often leading to impediments in wound healing. Addressing this, there is a critical demand… read more here.
Keywords: activation; infections diabetic; ros scavenging; drug resistant ... See more keywords
ROS-scavenging hydrogel to promote healing of bacteria infected diabetic wounds.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120286
Abstract: Bacterial infection has been a great threat to dermal wounds, especially to difficult-to-heal diabetic wounds. It is known that reactive oxygen species (ROS) generated by wounds or bacterial infection could further impede wound healing. Here,… read more here.
Keywords: bacterial infection; hydrogel; diabetic wounds; scavenging hydrogel ... See more keywords