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ROS/TXNIP pathway contributes to thrombin induced NLRP3 inflammasome activation and cell apoptosis in microglia.

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0 Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.02.019

Abstract: There is no effective therapy for intracerebral hemorrhage (ICH) because of poor understanding of the mechanisms of brain injury after hemorrhage. The NLRP3 inflammasome, as a vital component of innate immune system, which is associated… read more here.

Keywords: inflammasome activation; cell apoptosis; ros txnip; nlrp3 inflammasome ... See more keywords