Articles with "ros1 g2032" as a keyword



Photo from wikipedia

A novel ROS1 G2032 K missense mutation mediates lorlatinib resistance in a patient with ROS1-rearranged lung adenocarcinoma but responds to nab-paclitaxel plus pembrolizumab.

Sign Up to like & get
recommendations!
Published in 2020 at "Lung cancer"

DOI: 10.1016/j.lungcan.2020.03.019

Abstract: INTRODUCTION ROS1-rearranged non-small cell lung cancer (NSCLC) has demonstrated promising response to lorlatinib; however, no targeted therapy is available after failure of lorlatinib and information on acquired resistance mechanisms mediating lorlatinib resistance among ROS1-rearranged NSCLC… read more here.

Keywords: lorlatinib resistance; ros1; resistance; ros1 g2032 ... See more keywords